⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azepane SCHEMBL9536467 | 1.00 | — | — | |
| SCHEMBL7803628 | 1.00 | ALDH1A1 (0.90) | — | |
| SCHEMBL3689886 | 0.95 | ALDH1A1 (1.00) | — | |
| Piperidine SCHEMBL8435190 | 0.95 | ALDH1A1 (1.00) | — | |
| SCHEMBL3071895 | 0.95 | ALDH1A1 (1.00) | — | |
| SCHEMBL11508384 | 0.95 | ALDH1A1 (1.00) | — | |
| Piperidine SCHEMBL11283826 | 0.95 | — | — | |
| SCHEMBL21753221 | 0.95 | ALDH1A1 (1.00) | — | |
| Piperidine SCHEMBL21819962 | 0.95 | ALDH1A1 (1.00) | — | |
| SCHEMBL8253733 | 0.95 | ALDH1A1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2963 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4731611-A1 | TARGETED DEGRADERS OF HIV-1 NEF FOR THE TREATMENT OF HIV DISEASE | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2026-04-29 | — | — | EP | claimed |
| US-20260098040-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA CELLULAR THERAPIES INC (US) | 2026-04-09 | — | — | US | claimed |
| EP-3609891-B1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA CELLULAR THERAPIES INC (US) | 2026-02-11 | — | — | EP | claimed |
| US-20260022123-A1 | Methods of Making Modified BTK Inhibitors | PRINCIPIA BIOPHARMA INC. (US) | 2026-01-22 | — | — | US | claimed |
| EP-3898581-B1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA CELLULAR THERAPIES INC (US) | 2025-08-27 | — | — | EP | claimed |
| US-12358916-B2 | Substituted heterocycle fused gamma-carbolines synthesis | INTRA-CELLULAR THERAPIES, INC. (US) | 2025-07-15 | — | — | US | claimed |
| US-12297200-B2 | Substituted heterocycle fused gamma-carbolines synthesis | INTRA-CELLULAR THERAPIES, INC. (US) | 2025-05-13 | — | — | US | claimed |
| US-20250092042-A1 | HETEROARYL SUBSTITUTED SPIROPIPERIDINYL DERIVATIVES AND PHARMACEUTICAL USES THEREOF | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH, INC. | 2025-03-20 | — | — | US | claimed |
| CN-119528880-A | HIV-1 non-nucleoside reverse transcriptase inhibitor and preparation method and application thereof | 复旦大学 | 2025-02-28 | — | — | CN | claimed |
| WO-2025016066-A1 | ADHESIVE FOR SILICON-BASED NEGATIVE ELECTRODE ACTIVE MATERIAL, AND PREPARATION METHOD AND USE | 华为技术有限公司 | 2025-01-23 | — | — | WO | claimed |
| US-4518679-A | CONTAINING POLYALKYLPIPERIDINE CARBOXYLATED COMPOUNDS AS STABILIZERS | CIBA-GEIGY AG (CH) | 1985-05-21 | — | — | US | claimed |
| EP-0102034-A1 | Spiro(2H-1,4-benzodioxepin-3(5H)4'-piperidine and 3'-pyrrolidino) compounds, a process for preparing the same and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1984-03-07 | — | — | EP | claimed |
| EP-0005318-B1 | N-HETEROCYCLYL-4-PIPERIDINAMINES, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, INTERMEDIATES THEREFOR, AND METHOD FOR THE PREPARATION OF THE INTERMEDIATES | JANSSEN PHARMACEUTICA N.V. (BE) | 1982-01-06 | — | — | EP | claimed |
| US-4309546-A | Piperidino pyrrolidinones | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | claimed |
| US-4255301-A | HEAT RESISTANCE, PHOTOSTABILITY | ARGUS CHEMICAL CORPORATION (US) | 1981-03-10 | — | — | US | claimed |
| US-4225474-A | Organophosphonate coester stabilizers | ARGUS CHEMICAL CORP. (US) | 1980-09-30 | — | — | US | claimed |
| US-4200641-A | ANTIANAPHYLACTIC AGENTS, ANTIHISTAMINES | JANSSEN PHARMACEUTICA, N.V. (BE) | 1980-04-29 | — | — | US | claimed |
| EP-0006842-A1 | Organophosphonate co-ester, stabiliser composition containing it and synthetic resin stabilised therewith | S.A. Diamond Shamrock Benelux N.V. (BE) | 1980-01-23 | — | — | EP | claimed |
| EP-0005318-A1 | N-Heterocyclyl-4-piperidinamines, methods for their preparation, pharmaceutical compositions comprising them, intermediates therefor, and method for the preparation of the intermediates | JANSSEN PHARMACEUTICA N.V. (BE) | 1979-11-14 | — | — | EP | claimed |
| US-4124564-A | LIGHT AND HEAT RESISTANCE | ARGUS CHEMICAL CORPORATION (US) | 1978-11-07 | — | — | US | claimed |