Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.90 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL56256 | 1.00 | — | — | |
| Azepane SCHEMBL9536467 | 1.00 | — | — | |
| SCHEMBL3689886 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Piperidine SCHEMBL8435190 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| SCHEMBL3071895 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| SCHEMBL11508384 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Piperidine SCHEMBL11283826 | 0.95 | — | — | |
| SCHEMBL21753221 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Piperidine SCHEMBL21819962 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| SCHEMBL8253733 | 0.95 | ALDH1A1 (1.00) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119565-A1 | CYTOTOXIC ALKALOIDS (HALITULIN) | PHARMA MAR, S.A. (ES) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020411-A1 | CYTOTOXIC ALKALOIDS (HALITULIN) | PHARMA MAR, S.A. (ES) | 2000-04-13 | — | — | WO | disclosed |