Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA9 | Q16790 | 7/20 | 0.47 |
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA4 | P22748 | 3/20 | 0.47 |
| ▸ | CA6 | P23280 | 3/20 | 0.47 |
| ▸ | CA5A | P35218 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257964 | 0.84 | UHRF1 (0.52) | UHRF1CA1CA2CA9CA12 | |
| SCHEMBL5624211 | 0.73 | ALDH1A1 (0.45) | CA1CA2CA9CA12CA4 | |
| SCHEMBL3364318 | 0.69 | — | — | |
| SCHEMBL4152897 | 0.69 | — | — | |
| SCHEMBL30197278 | 0.69 | — | — | |
| SCHEMBL1458885 | 0.68 | GAA (0.32) | CA1CA2CA9CA12CA4 | |
| SCHEMBL1600771 | 0.67 | — | — | |
| SCHEMBL28874061 | 0.67 | PIK3CB (0.39) | UHRF1CA1CA2CA9CA12 | |
| SCHEMBL51542 | 0.67 | CA1 (0.61) | CA1CA2CA9CA12CA4 | |
| SCHEMBL21773201 | 0.67 | BCHE (0.33) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |
| US-7273863-B1 | Benzophenones as inhibitors of reverse transcriptase | SMITHKLINE BEECHAM CORPORATION (US) | 2007-09-25 | — | — | US | disclosed |
| EP-1710238-A1 | Benzophenones as inhibitors of reverse transcriptase | GLAXO GROUP LIMITED (GB) | 2006-10-11 | — | — | EP | disclosed |
| EP-1208091-B1 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | GLAXO GROUP LTD (GB) | 2006-05-03 | — | — | EP | disclosed |
| CN-1213038-C | Benzophenones as reverse transcriptase inhibitors | GLAXO GROUP LTD (GB) | 2005-08-03 | — | — | CN | disclosed |
| CN-1636986-A | Benzophenones as inhibitors of reverse transcriptase | GLAXO GROUP LTD (GB) | 2005-07-13 | — | — | CN | disclosed |
| CN-1636984-A | Benzophenones as inhibitors of reverse transcriptase | GLAXO GROUP LTD (GB) | 2005-07-13 | — | — | CN | disclosed |
| CN-1636985-A | Benzophenones as inhibitors of reverse transcriptase | GLAXO GROUP LTD (GB) | 2005-07-13 | — | — | CN | disclosed |
| CN-1391565-A | Benzophenones as reverse transcriptase inhibitors | GLAXO GROUP LTD (GB) | 2003-01-15 | — | — | CN | disclosed |
| EP-1208091-A1 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | GLAXO GROUP LIMITED (GB) | 2002-05-29 | — | — | EP | disclosed |
| WO-2001017982-A1 | BENZOPHENONES AS INHIBITORS OF REVERSE TRANSCRIPTASE | GLAXO GROUP LIMITED (GB) | 2001-03-15 | — | — | WO | disclosed |