Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3257964 | 0.83 | UHRF1 (0.52) | PIK3CBPI4KBPIK3CDPIK3CGPIP5K1C | |
| SCHEMBL16909250 | 0.80 | NOS3 (0.39) | PIK3CBPI4KBPIK3CDPIK3CGPIP5K1C | |
| SCHEMBL16234977 | 0.79 | PKM (0.43) | CA1CA2FYNKCNH2LMNA | |
| SCHEMBL26647261 | 0.76 | MAPT (0.43) | PIK3CBPI4KBPIK3CDPIK3CGPIP5K1C | |
| SCHEMBL19260832 | 0.73 | CA12 (0.36) | PIK3CBPI4KBPIK3CDPIK3CGPIP5K1C | |
| SCHEMBL14243224 | 0.71 | NOS3 (0.43) | PIK3CBPI4KBPIK3CDPIK3CGPIP5K1C | |
| SCHEMBL31035841 | 0.71 | ALOX5AP (0.40) | PIK3CBPI4KBPIK3CDPIK3CGPIP5K1C | |
| SCHEMBL7045227 | 0.71 | ALOX5AP (0.40) | PIK3CBPI4KBPIK3CDPIK3CGPIP5K1C | |
| SCHEMBL1492547 | 0.70 | CA12 (0.67) | PIK3CBPI4KBPIK3CDPIK3CGPIP5K1C | |
| SCHEMBL31279787 | 0.70 | CA12 (0.67) | PIK3CBPI4KBPIK3CDPIK3CGPIP5K1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109956927-A | Benzimidazoles derivative, preparation method and its in application pharmaceutically | 北京诺诚健华医药科技有限公司 | 2019-07-02 | — | — | CN | disclosed |