Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.54 |
| ▸ | CCR5 | P51681 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29690603 | 0.84 | PTGDR2 (0.55) | PTGDR2CCR5MAPTCYP1A2CYP3A4 | |
| SCHEMBL28943814 | 0.84 | PTGDR2 (0.55) | PTGDR2CCR5MAPTCYP1A2CYP3A4 | |
| SCHEMBL5627664 | 0.83 | CCR5 (0.64) | PTGDR2CCR5MAPTCYP1A2CYP3A4 | |
| SCHEMBL30866193 | 0.81 | CCR5 (0.62) | PTGDR2CCR5MAPTCYP1A2CYP3A4 | |
| SCHEMBL275887 | 0.81 | CCR5 (0.62) | PTGDR2CCR5MAPTCYP1A2CYP3A4 | |
| SCHEMBL23683243 | 0.80 | USP28 (0.56) | PTGDR2CCR5MAPTCYP1A2CYP3A4 | |
| SCHEMBL18001857 | 0.77 | PTPN1 (0.56) | PTGDR2CCR5MAPTCYP1A2CYP3A4 | |
| SCHEMBL16294120 | 0.76 | PTGDR2 (0.59) | PTGDR2CCR5MAPTCYP1A2CYP3A4 | |
| SCHEMBL29964454 | 0.76 | PTGDR2 (0.59) | PTGDR2CCR5MAPTCYP1A2CYP3A4 | |
| SCHEMBL29227151 | 0.75 | CCR5 (0.52) | PTGDR2CCR5MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082912-A1 | Pyrrole compounds for the treatment of prostaglandine mediated diseases | GLAXO GROUP LIMITED (GB) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070082912-A1 | Pyrrole compounds for the treatment of prostaglandine mediated diseases | PTGER1, PTGDR, PTGIR | PTGDR2 5/4885CCR5 1258/4885MAPT 4609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.