Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605792 | 1.00 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL31303946 | 0.84 | CYP3A4 (0.53) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL28609137 | 0.82 | RECQL (0.49) | CYP3A4CYP2C9RECQLAKR1C3MAPT | |
| SCHEMBL28609135 | 0.82 | RECQL (0.49) | CYP3A4CYP2C9RECQLAKR1C3MAPT | |
| SCHEMBL491485 | 0.81 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL560552 | 0.79 | CYP3A4 (0.63) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL3907078 | 0.77 | CYP3A4 (0.53) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL5913037 | 0.76 | CYP3A4 (0.66) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL7101790 | 0.76 | CYP3A4 (0.66) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 | |
| SCHEMBL261986 | 0.76 | CYP3A4 (0.66) | CYP3A4CYP2C9RECQLAKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200856-B | Trifluoromethyl propylene compound and preparation method and application thereof | 南京工业大学 | 2022-06-07 | — | — | CN | disclosed |
| CN-113200856-A | Trifluoromethyl propylene compound and preparation method and application thereof | 南京工业大学 | 2021-08-03 | — | — | CN | disclosed |
| US-8609318-B2 | Radiation-sensitive resin composition, method for forming resist pattern and polymer | JSR CORPORATION (JP) | 2013-12-17 | — | — | US | disclosed |
| US-20120034560-A1 | RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN AND POLYMER | JSR CORPORATION (JP) | 2012-02-09 | — | — | US | disclosed |