SCHEMBL560552

SCHEMBL560552

O=C(O)C(=Cc1ccccc1)CF

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.63
CYP2C9 P11712 1/20 0.63
RECQL P46063 1/20 0.52
AKR1C3 P42330 1/20 0.50
AKR1C1 Q04828 1/20 0.48
MME P08473 2/20 0.45
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TP53 P04637 1/20 0.42
ABAT P80404 1/20 0.42
HTT P42858 1/20 0.42
ALDH1A1 P00352 1/20 0.41
TSHR P16473 1/20 0.41
OPRK1 P41145 1/20 0.40
GRIK1 P39086 1/20 0.40
HAO1 Q9UJM8 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7101790 0.81 CYP3A4 (0.66) CYP3A4CYP2C9RECQLAKR1C3AKR1C1
SCHEMBL5913037 0.81 CYP3A4 (0.66) CYP3A4CYP2C9RECQLAKR1C3AKR1C1
SCHEMBL261986 0.81 CYP3A4 (0.66) CYP3A4CYP2C9RECQLAKR1C3AKR1C1
SCHEMBL8575022 0.80 CYP3A4 (0.59) CYP3A4CYP2C9RECQLAKR1C3AKR1C1
SCHEMBL57683 0.79 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3AKR1C1
SCHEMBL4327979 0.79 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3AKR1C1
SCHEMBL2918640 0.79 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3AKR1C1
SCHEMBL8041928 0.79 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3AKR1C1
SCHEMBL9068476 0.79 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3AKR1C1
SCHEMBL6529939 0.79 CYP3A4 (0.63) CYP3A4CYP2C9RECQLAKR1C3AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612145-B2 Composite material containing non-functional aromatic end group-containing polymer ROHM AND HAAS COMPANY (US) 2009-11-03 US claimed
EP-0745621-B1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optical use ESSILOR INT (FR) 1998-04-15 EP claimed
EP-0745621-A1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optional use ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP claimed
EP-1579521-B1 CURABLE COMPOSITION, CURED PRODUCT THEREOF, MOLDED PRODUCT THEREOF AND USE AS FUEL CELL SEPARATOR SHOWA DENKO KK (JP) 2018-04-11 EP disclosed
US-9823539-B2 Methods and systems for forming optical modulators using micro-contact lithography EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2017-11-21 US disclosed
US-20160139484-A1 METHODS AND SYSTEMS FOR FORMING OPTICAL MODULATORS USING MICRO-CONTACT LITHOGRAPHY EMPIRE TECHNOLOGY DEVELOPMENT LLC (DE) 2016-05-19 US disclosed
US-20160017076-A1 CURABLE COMPOSITION, TRANSPARENT HEAT-RESISTANT MATERIAL, AND USE THEREOF SHOWA DENKO K.K. (JP) 2016-01-21 US disclosed
WO-2014209294-A1 MICRO-CONTACT LITHOGRAPHY SYSTEMS FORMING OPTICAL MODULATORS EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2014-12-31 WO disclosed
US-8747703-B2 Electrically conducting curable resin composition, cured product thereof and method for producing the same SHOWA DENKO K.K. (JP) 2014-06-10 US disclosed
US-8609318-B2 Radiation-sensitive resin composition, method for forming resist pattern and polymer JSR CORPORATION (JP) 2013-12-17 US disclosed
US-8518524-B2 Transparent composite material SHOWA DENKO K.K. (JP) 2013-08-27 US disclosed
US-20050171270-A1 Conductive curable resin composition and separator for fuel cell SHOWA DENKO K.K. 2005-08-04 US disclosed
US-6472488-B2 MONOMERS CONTAIN THIO-CONTAINING HETEROCYCLES; USE IN MANUFACTURE OF WAVEGUIDES, OPTICAL FIBERS AND SPECTACLE LENSES ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2002-10-29 US disclosed
EP-0745621-B1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optical use ESSILOR INT (FR) 1998-04-15 EP disclosed
EP-0745620-B1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INT (FR) 1997-10-29 EP disclosed
EP-0745621-A1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optional use ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP disclosed
EP-0745620-A1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP disclosed
EP-0164019-B1 CLADDING MATERIALS FOR OPTICAL FIBERS Daikin Kogyo Co., Ltd. (JP) 1989-01-18 EP disclosed
US-4720428-A FLUOROACRYLATE POLYMER DAIKIN KOGYO CO., LTD. (JP) 1988-01-19 US disclosed
US-4554360-A DIARYLIODONIUM SALT, IODOARENE, COUPLING NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-11-19 US disclosed