Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A3 | P48764 | 13/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5628303 | 0.80 | SLC9A3 (0.46) | SLC9A3 | |
| SCHEMBL5628277 | 0.80 | SLC9A3 (0.41) | SLC9A3 | |
| SCHEMBL5629525 | 0.79 | SLC9A3 (0.50) | SLC9A3 | |
| SCHEMBL5630367 | 0.79 | SLC9A3 (0.50) | SLC9A3 | |
| SCHEMBL5628473 | 0.74 | SLC9A3 (0.62) | SLC9A3 | |
| SCHEMBL5631755 | 0.74 | SLC9A3 (0.62) | SLC9A3 | |
| Hydrochloric Acid SCHEMBL5628894 | 0.73 | SLC9A3 (0.61) | SLC9A3 | |
| SCHEMBL5628513 | 0.72 | SLC9A3 (0.46) | SLC9A3 | |
| SCHEMBL14462745 | 0.71 | SLC9A3 (0.55) | SLC9A3 | |
| SCHEMBL4034728 | 0.71 | SLC9A3 (0.50) | SLC9A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241775-B2 | Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-07-10 | — | — | US | disclosed |
| US-20050009863-A1 | Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009863-A1 | Composition, process of making, and medical use of substituted 4-phenyltetrahydroisoquinolines | CYP27A1, CYP11B2, CYP7A1 | SLC9A3 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.