Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | SI | P14410 | 6/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.46 |
| ▸ | PARP1 | P09874 | 6/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4716197 | 0.89 | PARP1 (0.46) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL4714942 | 0.80 | PARP1 (0.52) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL14587792 | 0.78 | PARP1 (0.50) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL14587799 | 0.78 | PARP1 (0.50) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL27961298 | 0.75 | ADORA1 (0.57) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL4715207 | 0.74 | GAA (0.54) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL14587779 | 0.74 | MGAM (0.50) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL4715338 | 0.73 | IDO1 (0.54) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL4714350 | 0.73 | KDM4E (0.55) | MGAMGAASIMGAM2PARP1 | |
| SCHEMBL1170768 | 0.72 | ADORA1 (0.61) | MGAMGAASIMGAM2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | ELAN PHARMACEUTICALS, INC. | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032475-A1 | Novel compounds useful for bradykinin B1 receptor antagonism | BDKRB1, BDKRB2, NPBWR1 | MGAM 4641/4885GAA 3511/4885SI 3857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.