Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28440897 | 0.86 | CYP1A2 (0.54) | APPMAPTCYP1A2CYP3A4GRM5 | |
| SCHEMBL7413841 | 0.82 | APP (0.52) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28622425 | 0.81 | HAO1 (0.50) | GRM5TSHRHAO1NR1H2CA1 | |
| SCHEMBL16439860 | 0.80 | APP (0.50) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL3432676 | 0.77 | GRM5 (0.37) | APPGRM5KDM4EHAO1NR1H2 | |
| SCHEMBL28579920 | 0.77 | APP (0.46) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL13471396 | 0.76 | ALDH1A1 (0.33) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22353122 | 0.75 | APP (0.59) | APPMAPTCYP3A4NPC1ALDH1A1 | |
| SCHEMBL28624467 | 0.75 | CYP2A6 (0.38) | ALDH1A1KDM4EHAO1CA1CA2 | |
| SCHEMBL31380183 | 0.75 | APP (0.36) | APPHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624520-A | Trifluoromethyl modified pyrenyl covalent organic framework material, and preparation method and application thereof | 中国石油大学(华东) | 2024-03-01 | — | — | CN | claimed |
| CN-116082390-A | Preparation method of diethyl zinc catalyzed organosilane compound | 北京理工大学 | 2023-05-09 | — | — | CN | claimed |
| CN-109851598-B | Preparation method of trifluoromethyl substituted trans enol ester | 江西师范大学 | 2022-11-29 | — | — | CN | claimed |
| CN-113024470-B | 4-perfluoroalkyl substituted pyrimidine compound and preparation method and application thereof | 南京工业大学 | 2022-05-24 | — | — | CN | claimed |
| CN-113548968-B | Method for synthesizing (Z) -olefin by nickel-catalyzed iron-mediated alkyne fluoroalkyl and product | 南京工业大学 | 2022-05-03 | — | — | CN | claimed |
| CN-109251192-B | Preparation method of 3-position or 4-position trifluoromethyl substituted isocoumarin | 江西师范大学 | 2022-03-04 | — | — | CN | claimed |
| CN-113548968-A | Method for synthesizing (Z) -olefin by nickel-catalyzed iron-mediated alkyne fluoroalkyl and product | 南京工业大学 | 2021-10-26 | — | — | CN | claimed |
| CN-113024470-A | 4-perfluoroalkyl substituted pyrimidine compound and preparation method and application thereof | 南京工业大学 | 2021-06-25 | — | — | CN | claimed |
| EP-3223328-B1 | ORGANIC PHOTOVOLTAIC CELL AND MANUFACTURING METHOD THEREOF | KOLON INC (KR) | 2020-07-29 | — | — | EP | claimed |
| CN-108690079-B | Fluorinated fluorescent phospholipid and synthesis method and application thereof | 中国科学院武汉物理与数学研究所 | 2020-01-24 | — | — | CN | claimed |
| US-20040159835-A1 | Memory device | CYPRESS SEMICONDUCTOR CORPORATION | 2004-08-19 | — | — | US | claimed |
| US-6768157-B2 | Memory device | ADVANCED MICRO DEVICES, INC. | 2004-07-27 | — | — | US | claimed |
| US-20040026729-A9 | Memory device | COATUE CORPORATION | 2004-02-12 | — | — | US | claimed |
| US-20030178667-A1 | Memory device | CYPRESS SEMICONDUCTOR CORPORATION | 2003-09-25 | — | — | US | claimed |
| US-20030155602-A1 | Memory device | COATUE CORPORATION | 2003-08-21 | — | — | US | claimed |
| CN-1103329-C | Ethynyl substituted aromatic compounds, their synthesis, polymers and uses thereof | DOW CHEMICAL CO (US) | 2003-03-19 | — | — | CN | claimed |
| EP-0854849-B1 | ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF | DOW CHEMICAL CO (US) | 2001-10-31 | — | — | EP | claimed |
| CN-1199389-A | Ethynyl substituted aromatic compounds, their synthesis, polymers and uses thereof | DOW CHEMICAL CO (US) | 1998-11-18 | — | — | CN | claimed |
| EP-0854849-A1 | ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF | THE DOW CHEMICAL COMPANY (US) | 1998-07-29 | — | — | EP | claimed |
| WO-1997010193-A1 | ETHYNYL SUBSTITUTED AROMATIC COMPOUNDS, SYNTHESIS, POLYMERS AND USES THEREOF | THE DOW CHEMICAL COMPANY (US) | 1997-03-20 | — | — | WO | claimed |