⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL3099935 | 0.80 | KDM4E (0.39) | — | |
| Morpholine SCHEMBL11338620 | 0.80 | MEN1 (0.55) | — | |
| SCHEMBL24849727 | 0.79 | CCR5 (0.39) | — | |
| SCHEMBL92627 | 0.79 | — | — | |
| SCHEMBL3192005 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL3198262 | 0.77 | LMNA (0.39) | — | |
| SCHEMBL17000126 | 0.77 | — | — | |
| SCHEMBL2181578 | 0.77 | — | — | |
| SCHEMBL16229248 | 0.77 | — | — | |
| SCHEMBL22685064 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016054123-A1 | METHODS OF PRODUCING HETEROPOLYCYCLES VIA BIS-EPOXIDATION | LIGHTNER DEREK (US) | 2016-04-07 | — | — | WO | claimed |
| US-9212161-B2 | Chiral synthesis of pyrrolidine core compounds en route to neuronal nitric oxide synthase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2015-12-15 | — | — | US | claimed |
| US-20140228578-A1 | Chiral Synthesis of Pyrrolidine Core Compounds en route to Neuronal Nitric Oxide Synthase Inhibitors | NORTHWESTERN UNIVERSITY (US) | 2014-08-14 | — | — | US | claimed |
| US-20120004415-A1 | Chiral Synthesis of Pyrrolidine Core Compounds en route to Neuronal Nitric Oxide Synthase Inhibitors | NORTHWESTERN UNIVERSITY | 2012-01-05 | — | — | US | claimed |
| WO-2012003427-A2 | CHIRAL SYNTHESIS OF PYRROLIDINE CORE COMPOUNDS EN ROUTE TO NEURONAL NITRIC OXIDE SYNTHASE INHIBITORS | NORTHWESTERN UNIVERSITY (US) | 2012-01-05 | — | — | WO | claimed |
| EP-0985664-B1 | Method of producing pyrrolidine derivatives | TORAY FINECHEMICALS CO LTD (JP) | 2004-03-31 | — | — | EP | claimed |
| US-6130338-A | OXIDATING THE CORRESPONDING 3-PYRROLINE COMPOUND TO GIVE AN EPOXYPYRROLIDINE COMPOUND | TORAY INDUSTRIES, INC. (JP) | 2000-10-10 | — | — | US | claimed |
| EP-0985664-A2 | Method of producing pyrrolidine derivatives | TORAY INDUSTRIES, INC. (JP) | 2000-03-15 | — | — | EP | claimed |
| EP-4402138-B1 | 3-PHENOXYAZETIDIN-1-YL-HETEROARYL PYRROLIDINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM INT (DE) | 2025-08-27 | — | — | EP | disclosed |
| US-12304902-B2 | Hydroxyheterocycloalkane-carbamoyl derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-05-20 | — | — | US | disclosed |
| US-12115157-B2 | 3-phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives and the use thereof as medicament | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2024-10-15 | — | — | US | disclosed |
| CN-114315679-B | Martinib chiral preparation method of intermediate | 杭州新博思生物医药有限公司 | 2024-08-30 | — | — | CN | disclosed |
| EP-4402138-A1 | 3-PHENOXYAZETIDIN-1-YL-HETEROARYL PYRROLIDINE DERIVATIVES AND THE USE THEREOF AS MEDICAMENT | Boehringer Ingelheim International GmbH (DE) | 2024-07-24 | — | — | EP | disclosed |
| CN-117940420-A | 3-Phenoxyazetidin-1-yl-heteroaryl pyrrolidine derivatives and their use as pharmaceuticals | 勃林格殷格翰国际有限公司 | 2024-04-26 | — | — | CN | disclosed |
| EP-0391132-A1 | 5-Alkylquinolinone carboxylic acids | BAYER AG (DE) | 1990-10-10 | — | — | EP | disclosed |
| EP-0350733-A2 | 7-(1-Pyrrolidinyl)-3-quinolone- and -naphthyridone-carboxylic-acid derivatives, method for their preparation and for substituted mono- and bi-cyclic pyrrolidine intermediates, and their antibacterial and feed additive compositions | BAYER AG (DE) | 1990-01-17 | — | — | EP | disclosed |
| EP-0302416-A1 | 2-nitroimidazole derivatives useful as radiosensitizers for hypoxic tumor cells | WARNER-LAMBERT COMPANY (US) | 1989-02-08 | — | — | EP | disclosed |
| US-4797397-A | X-RAYS THERAPY OF TUMORS | WARNER-LAMBERT COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| US-4251541-A | ANTIDEPRESSANTS | A. H. ROBINS COMPANY, INC. (US) | 1981-02-17 | — | — | US | disclosed |
| US-4230718-A | CATARACT PREVENTION IN DIABETIC ANIMALS; CHEMICAL INTERMEDIATES | A. H. ROBINS COMPANY, INC. (US) | 1980-10-28 | — | — | US | disclosed |