Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629612 | 1.00 | KDM4E (0.45) | KDM4EALDH1A1MAPTCYP1A2CYP3A4 | |
| SCHEMBL5630106 | 0.90 | HRH3 (0.46) | KDM4EALDH1A1MAPTHIF1AHRH3 | |
| SCHEMBL5630092 | 0.90 | HRH3 (0.46) | KDM4EALDH1A1MAPTHIF1AHRH3 | |
| SCHEMBL5627917 | 0.85 | KMT2A (0.46) | KDM4EALDH1A1MAPTHIF1ALMNA | |
| SCHEMBL5627928 | 0.85 | KMT2A (0.46) | KDM4EALDH1A1MAPTHIF1ALMNA | |
| SCHEMBL5629678 | 0.80 | TRPM8 (0.46) | ALDH1A1MAPTCYP1A2HIF1ALMNA | |
| SCHEMBL5629683 | 0.80 | TRPM8 (0.46) | ALDH1A1MAPTCYP1A2HIF1ALMNA | |
| SCHEMBL5626984 | 0.80 | HIF1A (0.42) | KDM4EALDH1A1MAPTHIF1AHRH3 | |
| SCHEMBL5626973 | 0.80 | HIF1A (0.42) | KDM4EALDH1A1MAPTHIF1AHRH3 | |
| SCHEMBL5743962 | 0.80 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2005-03-24 | — | — | US | claimed |
| US-7166620-B2 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2007-01-23 | — | — | US | disclosed |
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2005-03-24 | — | — | US | disclosed |
| EP-1453817-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003050096-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2003-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | CYP51A1, DPM1, GMDS | KDM4E 3501/4885ALDH1A1 362/4885MAPT 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.