Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5629767 | 1.00 | HIF1A (0.39) | HIF1ALMNAALDH1A1HTTKMT2A | |
| SCHEMBL6621199 | 0.82 | MAPT (0.36) | LMNAALDH1A1HTTKMT2AMAPT | |
| SCHEMBL5629678 | 0.81 | TRPM8 (0.46) | HIF1ALMNAALDH1A1HTTKMT2A | |
| SCHEMBL5629683 | 0.81 | TRPM8 (0.46) | HIF1ALMNAALDH1A1HTTKMT2A | |
| SCHEMBL5630092 | 0.81 | HRH3 (0.46) | HIF1AALDH1A1KMT2AMAPTHRH3 | |
| SCHEMBL5630106 | 0.81 | HRH3 (0.46) | HIF1AALDH1A1KMT2AMAPTHRH3 | |
| SCHEMBL5629612 | 0.77 | KDM4E (0.45) | HIF1ALMNAALDH1A1KMT2AMAPT | |
| SCHEMBL5629617 | 0.77 | KDM4E (0.45) | HIF1ALMNAALDH1A1KMT2AMAPT | |
| SCHEMBL8096246 | 0.76 | HIF1A (0.56) | HIF1AALDH1A1HTTKMT2AMAPT | |
| SCHEMBL8369944 | 0.76 | HIF1A (0.56) | HIF1AALDH1A1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2005-03-24 | — | — | US | claimed |
| EP-1453817-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | Isagro Ricerca S.r.l. (IT) | 2004-09-08 | — | — | EP | claimed |
| WO-2003050096-A1 | THIAZOLE DERIVATIVES WITH FUNGICIDAL ACTIVITY | ISAGRO RICERCA S.R.L. (IT) | 2003-06-19 | — | — | WO | claimed |
| US-7166620-B2 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2007-01-23 | — | — | US | disclosed |
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | ISAGRO RICERCA S.R.L. (IT) | 2005-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065197-A1 | Thiazole derivatives with fungicidal activity | CYP51A1, DPM1, GMDS | HIF1A 4700/4885LMNA 3981/4885ALDH1A1 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.