Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.49 |
| ▸ | EP300 | Q09472 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632127 | 1.00 | F10 (0.49) | F10EP300ALDH1A1MAPTKDM4E | |
| SCHEMBL5630997 | 0.97 | F10 (0.47) | F10EP300ALDH1A1MAPTKDM4E | |
| SCHEMBL5631123 | 0.97 | F10 (0.47) | F10EP300ALDH1A1MAPTKDM4E | |
| SCHEMBL6372830 | 0.89 | F10 (0.59) | F10EP300ALDH1A1MAPTKDM4E | |
| SCHEMBL5429259 | 0.89 | F10 (0.59) | F10EP300ALDH1A1MAPTKDM4E | |
| SCHEMBL5632358 | 0.87 | F10 (0.52) | F10EP300ALDH1A1MAPTKDM4E | |
| SCHEMBL5630404 | 0.87 | F10 (0.41) | F10EP300ALDH1A1MAPTNPC1 | |
| SCHEMBL5632366 | 0.86 | ALDH1A1 (0.46) | F10EP300ALDH1A1MAPTKDM4E | |
| SCHEMBL5631458 | 0.84 | F10 (0.42) | F10EP300ALDH1A1MAPTKDM4E | |
| SCHEMBL5631461 | 0.84 | F10 (0.61) | F10ALDH1A1MAPTNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183277-B2 | Alpha-((aryl or heteroaryl)ureido or carbamoyloxy)-N-heteroaryl amides; blood-coagulation factor Xa and VIIa inhibitors; synergistic mixtures with other antitumor agents or anticoagulants | MERCK PATENT GMBH (DE) | 2007-02-27 | — | — | US | claimed |
| US-20050171154-A1 | Carboxylic acid amides | MERCK PATENT GMBH (DE) | 2005-08-04 | — | — | US | claimed |
| US-7183277-B2 | Alpha-((aryl or heteroaryl)ureido or carbamoyloxy)-N-heteroaryl amides; blood-coagulation factor Xa and VIIa inhibitors; synergistic mixtures with other antitumor agents or anticoagulants | MERCK PATENT GMBH (DE) | 2007-02-27 | — | — | US | disclosed |
| US-20050171154-A1 | Carboxylic acid amides | MERCK PATENT GMBH (DE) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171154-A1 | Carboxylic acid amides | F11, F12, F2 | F10 4/4885EP300 984/4885ALDH1A1 378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.