SCHEMBL56316

SCHEMBL56316

CC(OCC(O)CO)=C(C)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.43
KDM4E B2RXH2 2/20 0.43
DUSP3 P51452 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
DGKA P23743 1/20 0.37
FAAH O00519 2/20 0.36
USP2 O75604 1/20 0.32
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30
CYP1A2 P05177 2/20 0.30
OR51E2 Q9H255 1/20 0.30
AGTR1 P30556 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8744237 0.82 KDM4E (0.42) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL49333 0.81 LMNA (0.41) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL7188587 0.79 KDM4E (0.44) LMNAKDM4EDUSP3MEN1KMT2A
Oxalic Acid SCHEMBL27467666 0.78 LMNA (0.44) LMNAKDM4EDUSP3MEN1KMT2A
Acetone SCHEMBL2900783 0.77 LMNA (0.47) LMNAKDM4EDUSP3MEN1KMT2A
Bicarbonate SCHEMBL3708813 0.77 LMNA (0.47) LMNAKDM4EDUSP3MEN1KMT2A
Acetic Acid SCHEMBL27581074 0.77 LMNA (0.47) LMNAKDM4EDUSP3MEN1KMT2A
SCHEMBL6665498 0.77 TSHR (0.48) LMNAKDM4EMEN1KMT2AALDH1A1
Acetic Acid SCHEMBL11226370 0.77 LMNA (0.47) LMNAKDM4EDUSP3MEN1KMT2A
Acetic Acid SCHEMBL25206 0.77 LMNA (0.47) LMNAKDM4EDUSP3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 350 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3969268-B1 METHOD FOR PRODUCING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2023-07-05 EP claimed
EP-2152224-B1 SELF-HEALING DENTAL COMPOSITES PREMIER DENTAL PRODUCTS CO (US) 2022-08-17 EP claimed
EP-2153811-B1 Single-part, light-curable, self-adhering dental restorative composition KERR CORP (US) 2020-03-04 EP claimed
EP-2979680-B1 DENTAL CURING COMPOSITION SHOFU KK (JP) 2019-11-13 EP claimed
US-9931281-B2 Multi-functional self-healing dental composites, methods of synthesis and methods of use ADA FOUNDATION (US) 2018-04-03 US claimed
EP-2578200-B1 Compounds for infiltrating and/or sealing of dental hard substance and method VOCO GMBH (DE) 2018-03-28 EP claimed
EP-2374444-B1 Dental covering material VOCO GMBH (DE) 2017-03-01 EP claimed
US-20160193119-A1 MULTI-FUNCTIONAL SELF-HEALING DENTAL COMPOSITES, METHODS OF SYNTHESIS AND METHODS OF USE ADA FOUNDATION (US) 2016-07-07 US claimed
EP-2047837-B1 Dental adhesive and use thereof KERR CORP (US) 2016-04-13 EP claimed
US-9119774-B2 Self-healing dental restorative formulations and related methods PREMIER DENTAL PRODUCTS COMPANY (US) 2015-09-01 US claimed
US-5859089-A COMPOSITE RESIN/GLASS IONOMER HYBRID TYPE; CONTAINS AN AROMATIC-MOIETY-CONTAINING POLYMERIZABLE RESIN, A FINELY DIVIDED ION-LEACHABLE FLUOROALUMINOSILICATE GLASS FILLER AND A POLYMERIZATION INITIATOR SYSTEM THE KERR CORPORATION (US) 1999-01-12 US claimed
US-5401783-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1995-03-28 US claimed
US-5270351-A Adhesion-promoting agents incorporating polyvalent cations AMERICAN DENTAL ASSOCIATION HEALTH FOUNDATION (US) 1993-12-14 US claimed
US-5109089-A RADIATION-CURABLE LIQUID RESIN FOR SECONDARY COATING OF LIGHTWAVE GUIDES SIEMENS AKTIENGESELLSCHAFT (DE) 1992-04-28 US claimed
US-5057587-A RADIATION-CURABLE LIQUID RESIN FOR SECONDARY COATING OF LIGHTWAVE GUIDES SIEMENS AKTIENGESELLSCHAFT (DE) 1991-10-15 US claimed
US-4330657-A Process for the production of storage-stable urethane acryls CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) 1982-05-18 US claimed
US-3993663-A POLYCYCLOACETAL, ESTER, ALCOHOL SHOWA HIGH POLYMER CO., LTD. (JA) 1976-11-23 US claimed
US-3978155-A CURABLE RESINOUS COMPOSITION COMPRISING COMBINATION OF POLYMERIZABLE CYCLOACETAL COMPOUND WITH UNSATURATED POLYESTER SHOWA HIGH POLYMER CO., LTD. (JA) 1976-08-31 US claimed
US-3933857-A Polymerizable cycloacetal resinous composition SHOWA HIGHPOLYMER CO., LTD. (JA) 1976-01-20 US claimed
US-3931353-A Polymerizable cycloacetal resinous composition SHOWA HIGH POLYMER CO., LTD. (JA) 1976-01-06 US claimed