Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56316 | 0.79 | LMNA (0.43) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL5166839 | 0.79 | TSHR (0.44) | LMNA | |
| SCHEMBL5168881 | 0.79 | TSHR (0.44) | LMNA | |
| SCHEMBL8744237 | 0.78 | KDM4E (0.42) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Propionic Acid SCHEMBL27474994 | 0.76 | LMNA (0.47) | KDM4EDUSP3MEN1KMT2ALMNA | |
| Oxalic Acid SCHEMBL28313461 | 0.76 | KDM4E (0.56) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL126032 | 0.74 | ALDH1A1 (0.46) | KDM4ELMNA | |
| SCHEMBL222774 | 0.74 | ALDH1A1 (0.46) | KDM4ELMNA | |
| Methacrylic Acid SCHEMBL2830657 | 0.74 | KDM4E (0.50) | KDM4EDUSP3MEN1KMT2ALMNA | |
| SCHEMBL8982156 | 0.73 | ACHE (0.36) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747442-B1 | Modified aqueous polyurethane dispersions and methods for making same | NAT STARCH CHEM INVEST (US) | 2003-09-03 | — | — | EP | disclosed |
| US-5945473-A | Modified aqueous polyurethane dispersions and methods for making same | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1999-08-31 | — | — | US | disclosed |
| EP-0747442-A2 | Modified aqueous polyurethane dispersions and methods for making same | National Starch and Chemical Investment Holding Corporation (US) | 1996-12-11 | — | — | EP | disclosed |