Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633743 | 0.78 | PLA2G2A (0.43) | PLA2G2AKMT2ATSHRLMNAHSD17B10 | |
| SCHEMBL5632108 | 0.78 | PPARD (0.51) | LMNATP53NPC1MAPTSMN1; SMN2 | |
| SCHEMBL5634093 | 0.78 | PPARA (0.54) | — | |
| SCHEMBL5631214 | 0.78 | POLQ (0.50) | CYP2C9CYP2C19 | |
| SCHEMBL5702296 | 0.77 | PLA2G4B (0.54) | KMT2ALMNAMEN1PLA2G4BMAPT | |
| SCHEMBL4806424 | 0.74 | CYP2D6 (0.50) | KMT2ATSHRLMNACYP1A2CYP2C9 | |
| SCHEMBL5632046 | 0.74 | TOP2A (0.41) | KMT2ALMNAMEN1HTTTP53 | |
| SCHEMBL5633651 | 0.74 | LMNA (0.38) | HCAR3LMNACYP1A2HTTBCHE | |
| SCHEMBL12396413 | 0.72 | FFAR1 (0.61) | LMNA | |
| SCHEMBL12396414 | 0.72 | FFAR1 (0.69) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208026-A1 | N-Containing Heteroaromatic Compounds As Modulators Of Ppars And Methods Of Treating Metabolic Disorders | KALYPSYS, INC. | 2007-09-06 | — | — | US | disclosed |
| US-20070208026-A1 | N-Containing Heteroaromatic Compounds As Modulators Of Ppars And Methods Of Treating Metabolic Disorders | KALYPSYS, INC. | 2007-09-06 | — | — | US | disclosed |
| US-20070208026-A1 | N-Containing Heteroaromatic Compounds As Modulators Of Ppars And Methods Of Treating Metabolic Disorders | KALYPSYS, INC. | 2007-09-06 | — | — | US | disclosed |
| WO-2004092130-A2 | N-CONTAINING HETEROAROMATIC COMPOUNDS AS MODULATORS OF PPARS AND METHODS OF TREATING METABOLIC DISORDERS | KALYPSYS, INC. (US) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208026-A1 | N-Containing Heteroaromatic Compounds As Modulators Of Ppars And Methods Of Treating Metabolic Disorders | PPARG, PPARA, PPARD | HCAR3 683/4885PLA2G2A 1282/4885KMT2A 3055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.