SCHEMBL5633144

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5959841	0.89	KDR (0.48)	KDREPHB4TEKBRAFTHRA
	SCHEMBL5959828	0.86	KDR (0.44)	KDREPHB4TEKNTRK1NTRK2
	SCHEMBL5612143	0.83	EPHB4 (0.52)	KDREPHB4TEKPDGFRBBRAF
	SCHEMBL5636147	0.83	KDR (0.51)	KDREPHB4CDK8BRAFTHRA
	SCHEMBL5592723	0.81	RIPK1 (0.46)	KDREPHB4TEKBRAFFLT3
	SCHEMBL5586028	0.80	BRAF (0.52)	KDREPHB4BRAFCA9FLT1
	SCHEMBL5959801	0.78	RAF1 (0.42)	KDREPHB4TEKNTRK1BRAF
	SCHEMBL5592608	0.78	KDR (0.48)	KDREPHB4TEKNTRK1NTRK2
	SCHEMBL5592591	0.77	KCNQ3 (0.58)	KDREPHB4TEKNTRK1NTRK2
	SCHEMBL5592906	0.77	KMT2A (0.50)	EPHB4IDH1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.