Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632894 | 0.87 | CYP1A2 (0.40) | TGM2ALDH1A1SMN1; SMN2POLBHTT | |
| SCHEMBL5633577 | 0.87 | HTT (0.49) | DPP8TGM2MAPTSMN1; SMN2LMNA | |
| SCHEMBL13647947 | 0.81 | MGLL (0.67) | DPP8DPP9MGLLTGM2ALDH1A1 | |
| SCHEMBL10500161 | 0.74 | DPP8 (0.58) | DPP8DPP9MGLLTGM2ALDH1A1 | |
| SCHEMBL6418689 | 0.73 | DPP8 (0.58) | DPP8DPP9MGLLTGM2ALDH1A1 | |
| SCHEMBL6624294 | 0.72 | DPP8 (0.57) | DPP8DPP9MGLLTGM2ALDH1A1 | |
| SCHEMBL10825541 | 0.72 | DPP8 (0.57) | DPP8DPP9MGLLTGM2ALDH1A1 | |
| SCHEMBL11391394 | 0.72 | DPP8 (0.57) | DPP8DPP9MGLLTGM2ALDH1A1 | |
| SCHEMBL6397257 | 0.72 | DPP8 (0.57) | DPP8DPP9MGLLTGM2ALDH1A1 | |
| SCHEMBL4972414 | 0.72 | ALDH1A1 (0.53) | DPP8DPP9TGM2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070123548-A1 | Pth agonists | COWAN DAVID J | 2007-05-31 | — | — | US | claimed |
| US-20070123548-A1 | Pth agonists | COWAN DAVID J | 2007-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123548-A1 | Pth agonists | PTH1R, SSTR3, CALCR | DPP8 2239/4885DPP9 3806/4885MGLL 4436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.