SCHEMBL5633469 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	CA12	O43570	12/20	0.41

▸	CA1	P00915	11/20	0.41

▸	CA2	P00918	11/20	0.41

▸	C5AR1	P21730	1/20	0.40

▸	CA4	P22748	4/20	0.40

▸	LDHA	P00338	1/20	0.39

▸	RORC	P51449	3/20	0.37

▸	CA9	Q16790	1/20	0.37

▸	PTGS2	P35354	1/20	0.37

▸	ADORA3	P0DMS8	1/20	0.37

▸	ADORA2B	P29275	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5134923	0.91	CA12 (0.41)	CA12CA1CA2C5AR1CA4
SCHEMBL5136767	0.91	C5AR1 (0.41)	CA12CA1CA2C5AR1CA4
SCHEMBL647835	0.88	C5AR1 (0.42)	CA12CA1CA2C5AR1CA4
SCHEMBL649150	0.88	C5AR1 (0.41)	CA12CA1CA2C5AR1CA4
SCHEMBL650800	0.88	C5AR1 (0.45)	CA12CA1CA2C5AR1CA4
SCHEMBL5138126	0.88	CA2 (0.41)	CA12CA1CA2C5AR1CA4
SCHEMBL652063	0.86	C5AR1 (0.40)	CA12CA1CA2C5AR1CA4
SCHEMBL649773	0.86	C5AR1 (0.42)	CA12CA1CA2C5AR1CA4
SCHEMBL1912981	0.85	DAGLA (0.40)	CA12CA1CA2C5AR1CA4
SCHEMBL1912982	0.85	TRPM8 (0.44)	C5AR1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7186734-B2	Aryl imidazoles and related compounds as C5a receptor modulators	NEUROGEN CORPORATION (US)	2007-03-06	—	—	US	disclosed