Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634216 | 0.92 | HTT (0.49) | OPRK1ALDH1A1KDM4EDRD2DRD3 | |
| SCHEMBL4776245 | 0.90 | OPRK1 (0.53) | OPRK1ALDH1A1KDM4EDRD2DRD3 | |
| SCHEMBL5633241 | 0.88 | OPRK1 (0.48) | OPRK1ALDH1A1DRD2DRD3MAPT | |
| SCHEMBL354877 | 0.87 | OPRK1 (0.50) | OPRK1ALDH1A1POLBDRD2DRD3 | |
| SCHEMBL354878 | 0.87 | OPRK1 (0.50) | OPRK1ALDH1A1POLBDRD2DRD3 | |
| SCHEMBL1725336 | 0.86 | OPRK1 (0.49) | OPRK1ALDH1A1KDM4EPOLBDRD2 | |
| SCHEMBL354963 | 0.86 | OPRK1 (0.49) | OPRK1ALDH1A1KDM4EPOLBDRD2 | |
| SCHEMBL354962 | 0.86 | OPRK1 (0.49) | OPRK1ALDH1A1KDM4EPOLBDRD2 | |
| SCHEMBL5634205 | 0.85 | LMNA (0.49) | OPRK1DRD2DRD3PLAU | |
| SCHEMBL5632913 | 0.85 | HTT (0.59) | OPRK1ALDH1A1KDM4EPOLBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304065-B2 | Melanin concentrating hormone antagonists | THE PROCTER & GAMBLE COMPANY (US) | 2007-12-04 | — | — | US | claimed |