Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633685 | 0.95 | CCR5 (0.54) | CCR5KCNH2 | |
| SCHEMBL5633851 | 0.93 | CCR5 (0.52) | CCR5KCNH2 | |
| SCHEMBL5634151 | 0.93 | CCR5 (0.59) | CCR5KCNH2 | |
| SCHEMBL5633684 | 0.93 | CCR5 (0.51) | CCR5KCNH2 | |
| SCHEMBL5633692 | 0.93 | CCR5 (0.51) | CCR5KCNH2 | |
| SCHEMBL5635539 | 0.90 | CCR5 (0.73) | CCR5KCNH2 | |
| SCHEMBL5634369 | 0.90 | CCR5 (0.73) | CCR5KCNH2 | |
| SCHEMBL5634195 | 0.89 | CCR5 (0.67) | CCR5KCNH2 | |
| SCHEMBL5633888 | 0.89 | CCR5 (0.59) | CCR5KCNH2 | |
| SCHEMBL5634122 | 0.89 | CCR5 (0.47) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | claimed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-20010039026-A1 | Assay method | PFIZER INC. | 2001-11-08 | — | — | US | disclosed |
| EP-1118858-A2 | Assay method | Pfizer Limited (GB) | 2001-07-25 | — | — | EP | disclosed |