Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 18/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633870 | 0.95 | CCR5 (0.60) | CCR5KCNH2 | |
| SCHEMBL5633851 | 0.91 | CCR5 (0.52) | CCR5KCNH2 | |
| SCHEMBL5633692 | 0.91 | CCR5 (0.51) | CCR5KCNH2 | |
| SCHEMBL5633684 | 0.91 | CCR5 (0.51) | CCR5KCNH2 | |
| SCHEMBL5635173 | 0.90 | CCR5 (0.65) | CCR5KCNH2 | |
| SCHEMBL5661678 | 0.90 | CCR5 (0.65) | CCR5KCNH2 | |
| SCHEMBL5634879 | 0.88 | CCR5 (0.58) | CCR5KCNH2 | |
| SCHEMBL5634151 | 0.88 | CCR5 (0.59) | CCR5KCNH2 | |
| SCHEMBL5634122 | 0.87 | CCR5 (0.47) | CCR5KCNH2 | |
| SCHEMBL5634675 | 0.86 | CCR5 (0.46) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | claimed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-20010039026-A1 | Assay method | PFIZER INC. | 2001-11-08 | — | — | US | disclosed |
| EP-1118858-A2 | Assay method | Pfizer Limited (GB) | 2001-07-25 | — | — | EP | disclosed |