Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 13/20 | 0.53 |
| ▸ | PRCP | P42785 | 5/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5633911 | 1.00 | CCR5 (0.53) | CCR5PRCPTUBB4ATUBBTUBA3C | |
| SCHEMBL5634436 | 0.94 | CCR5 (0.59) | CCR5PRCPTUBB4ATUBBTUBA3C | |
| SCHEMBL5634441 | 0.94 | CCR5 (0.59) | CCR5PRCPTUBB4ATUBBTUBA3C | |
| SCHEMBL5635080 | 0.90 | CCR5 (0.49) | CCR5PRCPTUBB4ATUBBTUBA3C | |
| SCHEMBL5634879 | 0.90 | CCR5 (0.58) | CCR5PRCPKCNH2 | |
| SCHEMBL14514105 | 0.89 | CCR5 (0.48) | CCR5PRCPTUBB4ATUBBTUBA3C | |
| SCHEMBL5633684 | 0.87 | CCR5 (0.51) | CCR5PRCPKCNH2 | |
| SCHEMBL5633692 | 0.87 | CCR5 (0.51) | CCR5PRCPKCNH2 | |
| SCHEMBL5633782 | 0.86 | CCR5 (0.51) | CCR5KCNH2 | |
| SCHEMBL5633777 | 0.86 | CCR5 (0.51) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |