Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.57 |
| ▸ | GRM6 | O15303 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | GRM8 | O00222 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.45 |
| ▸ | RELA | Q04206 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56061 | 0.86 | GRM4 (0.58) | GRM4GRM6FOLH1GRM8CETP | |
| SCHEMBL57177 | 0.85 | SLC7A5 (0.47) | GRM4GRM6SLC7A5FOLH1GRM8 | |
| SCHEMBL55394 | 0.83 | FOLH1 (0.49) | GRM4GRM6FOLH1GRM8CETP | |
| SCHEMBL4084499 | 0.81 | GRM4 (0.67) | GRM4GRM6SLC7A5FOLH1GRM8 | |
| SCHEMBL56601 | 0.77 | SLC1A5 (0.46) | GRM4GRM6FOLH1GRM8RAB9A | |
| SCHEMBL56051 | 0.77 | FOLH1 (0.46) | GRM4GRM6FOLH1GRM8CETP | |
| SCHEMBL1456419 | 0.77 | MRGPRX4 (0.56) | MRGPRX4FOLH1TP53PKMNFKB1 | |
| SCHEMBL57236 | 0.76 | GRM8 (0.62) | GRM4GRM6GRM8SMN1; SMN2RAB9A | |
| SCHEMBL25355590 | 0.76 | ANPEP (0.55) | GRM4SLC7A5FOLH1 | |
| SCHEMBL25355588 | 0.76 | ANPEP (0.55) | GRM4SLC7A5FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129557-B2 | Phosphonic acid diester derivative and method for producing thereof | Nagai, Kazuhiro (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | HIRATAKE, GOU (JP) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163725-A1 | PHOSPHONIC ACID DIESTER DERIVATIVE AND METHOD FOR PRODUCING THEREOF | PPA1, G6PD, PHOSPHO1 | GRM4 4122/4885GRM6 3489/4885MRGPRX4 4061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.