Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 4/20 | 0.67 |
| ▸ | GRM6 | O15303 | 2/20 | 0.67 |
| ▸ | GRM8 | O00222 | 1/20 | 0.67 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.47 |
| ▸ | GLUL | P15104 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56343 | 0.81 | GRM4 (0.57) | GRM4GRM6GRM8FOLH1SLC7A5 | |
| SCHEMBL10000471 | 0.80 | GRM4 (1.00) | GRM4GRM6GRM8 | |
| SCHEMBL25355590 | 0.79 | ANPEP (0.55) | GRM4FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL25355588 | 0.79 | ANPEP (0.55) | GRM4FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL4101257 | 0.75 | GRM4 (1.00) | GRM4GRM6GRM8 | |
| SCHEMBL321517 | 0.75 | SLC7A5 (0.70) | FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL1061213 | 0.75 | SLC7A5 (0.70) | FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL29430350 | 0.75 | SLC7A5 (0.70) | FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL1061212 | 0.75 | SLC7A5 (0.70) | FOLH1SLC7A5ANPEPENPEP | |
| SCHEMBL914724 | 0.75 | FOLH1 (0.60) | FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-07-02 | — | — | US | disclosed |
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-07-02 | — | — | US | disclosed |
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2009-07-02 | — | — | US | disclosed |
| EP-1937699-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007052169-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007052169-A2 | HYPOPHOSPHOROUS ACID DERIVATIVES AND THEIR THERAPEUTICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090170813-A1 | Hypophosphorous Acid Derivatives and their Therapeutical Applications | P4HA1, CYP2R1, EGLN3 | GRM4 1497/4885GRM6 1170/4885GRM8 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.