Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 18/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14514118 | 1.00 | CCR5 (0.61) | CCR5 | |
| SCHEMBL14514119 | 0.85 | CCR5 (0.70) | CCR5 | |
| SCHEMBL5634305 | 0.83 | CTSL (0.51) | CCR5 | |
| SCHEMBL5861206 | 0.82 | CCR5 (0.69) | CCR5 | |
| SCHEMBL5861294 | 0.82 | CCR5 (0.69) | CCR5 | |
| SCHEMBL6699449 | 0.81 | CCR5 (0.69) | CCR5 | |
| SCHEMBL5860806 | 0.81 | CCR5 (0.87) | CCR5 | |
| SCHEMBL4693379 | 0.80 | CCR5 (0.72) | CCR5 | |
| SCHEMBL5634565 | 0.80 | EGFR (0.48) | CCR5 | |
| SCHEMBL14514117 | 0.80 | EGFR (0.48) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217714-B1 | CCR5 modulators | AGOURON PHARMACEUTICALS, INC. (US) | 2007-05-15 | — | — | US | disclosed |