SCHEMBL5634992

SCHEMBL5634992

CC=CC(=O)NCCC[Si](OCCOC)(OCCOC)OCCOC

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.44
HPGD P15428 3/20 0.40
CYP2C19 P33261 1/20 0.40
APEX1 P27695 1/20 0.39
BRD4 O60885 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
TSHR P16473 1/20 0.37
GLA P06280 1/20 0.36
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
TYR P14679 1/20 0.35
HTR1A P08908 2/20 0.33
HTR2C P28335 2/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33
HTR7 P34969 1/20 0.33
HTR6 P50406 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29573387 0.83 ZDHHC20 (0.47) CYP1A2HPGDCYP2C19MEN1KMT2A
SCHEMBL1081176 0.83 APEX1 (0.39) CYP1A2APEX1BRD4SMN1; SMN2MEN1
SCHEMBL1078311 0.82 SMN1; SMN2 (0.46) CYP1A2HPGDAPEX1BRD4SMN1; SMN2
SCHEMBL28289079 0.82 CYP1A2 (0.55) CYP1A2HPGDCYP2C19APEX1SMN1; SMN2
SCHEMBL29470599 0.78 HPGD (0.51) CYP1A2HPGDCYP2C19APEX1SMN1; SMN2
SCHEMBL2400469 0.78 TSHR (0.35) TSHRALDH1A1
SCHEMBL73426 0.77 ATM (0.41) HPGDSMN1; SMN2TSHRALDH1A1LMNA
SCHEMBL1081177 0.76 APEX1 (0.39) CYP1A2APEX1BRD4SMN1; SMN2MEN1
SCHEMBL25207949 0.76 HPGD (0.43) CYP1A2HPGDCYP2C19APEX1BRD4
SCHEMBL19712269 0.75 APEX1 (0.38) APEX1BRD4SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309746-B2 Polymers containing silane WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2007-12-18 US disclosed
US-20060194006-A1 Compound of a powdery coating agent WACKER CHEMIE AG (DE) 2006-08-31 US disclosed
US-7052773-B2 Silane-modified polyvinyl alcohol mixtures WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2006-05-30 US disclosed
US-20050182223-A1 Polymers containing silane WACKER CHEMIE AG (DE) 2005-08-18 US disclosed
US-20040014857-A1 Silane-containing polyvinyl alcohol for coating slips WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2004-01-22 US disclosed
US-20040013888-A1 Silane-modified polyvinyl alcohol mixtures WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2004-01-22 US disclosed