Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4026815 | 0.92 | MC4R (0.40) | MC4RNTRK1KMT2AMEN1KDM4E | |
| SCHEMBL4780053 | 0.91 | MC4R (0.44) | MC4RNTRK1KMT2AMEN1KDM4E | |
| SCHEMBL4019465 | 0.88 | MC4R (0.42) | MC4RNTRK1KMT2AMEN1KDM4E | |
| SCHEMBL4019468 | 0.88 | MC4R (0.42) | MC4RNTRK1KMT2AMEN1KDM4E | |
| SCHEMBL4751807 | 0.88 | MC4R (0.42) | MC4RNTRK1KMT2AMEN1KDM4E | |
| SCHEMBL4021775 | 0.87 | NPC1 (0.35) | MC4REEDNTRK1NPC1ACKR3 | |
| SCHEMBL4749170 | 0.85 | MC4R (0.40) | MC4RNTRK1KMT2AMEN1KDM4E | |
| SCHEMBL4029258 | 0.85 | MC4R (0.40) | MC4RNTRK1KMT2AMEN1KDM4E | |
| SCHEMBL4776626 | 0.83 | MC4R (0.44) | MC4RNTRK1KMT2AMEN1KDM4E | |
| SCHEMBL4776650 | 0.83 | MC4R (0.44) | MC4RNTRK1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. | 2007-07-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161674-A1 | Certain chemical entities, compositions, and methods | TP53, VHL, RB1 | MC4R 3874/4885EED 1022/4885NTRK1 3738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.