Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 6/20 | 0.37 |
| ▸ | HTR2C | P28335 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635355 | 0.94 | USP30 (0.40) | USP30IDO1TDO2PIK3CAHTR2A | |
| SCHEMBL5637607 | 0.94 | USP30 (0.40) | USP30IDO1TDO2PIK3CAHTR2A | |
| SCHEMBL5635404 | 0.93 | USP30 (0.39) | USP30HTR2AHTR2CRECQLGPR119 | |
| SCHEMBL6491628 | 0.84 | USP30 (0.42) | USP30IDO1TDO2PIK3CAHTR2A | |
| SCHEMBL6491629 | 0.84 | USP30 (0.42) | USP30IDO1TDO2PIK3CAHTR2A | |
| SCHEMBL6756087 | 0.84 | HTR2A (0.41) | HTR2AHTR2CDRD2HTR1ADRD4 | |
| SCHEMBL5421540 | 0.82 | USP30 (0.41) | USP30IDO1TDO2HTR2AHTR2C | |
| SCHEMBL5848252 | 0.82 | USP30 (0.41) | USP30IDO1TDO2HTR2AHTR2C | |
| SCHEMBL5635971 | 0.82 | USP30 (0.47) | USP30HTR2AHTR2CDRD2MAPT | |
| SCHEMBL5637776 | 0.81 | USP30 (0.49) | USP30HTR2AHTR2CDRD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39679-E1 | Substituted heterocycle fused gamma-carbolines | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-06-05 | — | — | US | disclosed |
| US-6713471-B1 | SUCH AS TERT-BUTYL-1-METHYL-6,7,9,12-TETRAHYDRO-5H-PYRIDO-(4,3-B)(1,4) THIAZEPINO(2,3,4-HI)INDOLE-11(10H)-CARBOXYLATE; SEROTONIN AGONISTS AND ANTAGONISTS; CENTRAL NERVOUS SYSTEM DISORDERS | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2004-03-30 | — | — | US | disclosed |