SCHEMBL7060302

SCHEMBL7060302

CCOC(=O)[C@H](C)NC=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ALDH1A1 P00352 2/20 0.39
ADH1B P00325 2/20 0.39
ADH1C P00326 2/20 0.39
ADH1A P07327 2/20 0.39
METAP2 P50579 8/20 0.38
METAP1 P53582 6/20 0.38
PKM P14618 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GLO1 Q04760 1/20 0.38
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
CNR1 P21554 1/20 0.36
DAGLA Q9Y4D2 1/20 0.36
ALOX15 P16050 1/20 0.36
SOAT1 P35610 1/20 0.36
ADH4 P08319 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5527208 1.00 MGAM (0.41) MGAMGAASIMGAM2ALDH1A1
SCHEMBL23044882 0.83 HCAR2 (0.38) ALDH1A1ADH1BADH1CADH1ANPSR1
SCHEMBL11026074 0.83 HCAR2 (0.38) ALDH1A1ADH1BADH1CADH1ANPSR1
SCHEMBL14412682 0.83 ADH1B (0.39) ADH1BADH1CADH1ACNR1DAGLA
SCHEMBL11508858 0.83 MGAM (0.41) MGAMGAASIMGAM2ALDH1A1
SCHEMBL11511632 0.83 MGAM (0.41) MGAMGAASIMGAM2ALDH1A1
SCHEMBL11027872 0.81 TSHR (0.45) ALDH1A1ADH1BADH1CADH1AHSD17B10
SCHEMBL17287125 0.80 ATM (0.47) ALDH1A1ADH1BADH1CADH1ANPSR1
SCHEMBL6826472 0.80 ATM (0.47) ALDH1A1ADH1BADH1CADH1ANPSR1
SCHEMBL6826471 0.80 ATM (0.47) ALDH1A1ADH1BADH1CADH1ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112694450-B Preparation method of 4-methyl-5-ethoxy oxazole 浙江圣达生物药业股份有限公司 2022-06-21 CN claimed
WO-2021037022-A1 METHOD FOR PREPARING 4-METHYL-5-ALKOXY OXAZOLE 山东新和成精化科技有限公司 2021-03-04 WO claimed
CN-110423226-B Preparation method of 4-methyl-5-alkoxy oxazole 山东新和成精化科技有限公司 2021-01-05 CN claimed
CN-114702405-A Preparation method of N-ethoxy oxalyl alanine ethyl ester 浙江花园营养科技有限公司 2022-07-05 CN disclosed
CN-114671823-A Preparation method of 4-methyl-5-ethoxy oxazole acid ethyl ester 浙江花园营养科技有限公司 2022-06-28 CN disclosed
CN-112694450-B Preparation method of 4-methyl-5-ethoxy oxazole 浙江圣达生物药业股份有限公司 2022-06-21 CN disclosed
CN-112694450-B Preparation method of 4-methyl-5-ethoxy oxazole 浙江圣达生物药业股份有限公司 2022-06-21 CN disclosed
CN-112694450-A Preparation method of 4-methyl-5-ethoxy oxazole 浙江圣达生物药业股份有限公司 2021-04-23 CN disclosed
WO-2021037022-A1 METHOD FOR PREPARING 4-METHYL-5-ALKOXY OXAZOLE 山东新和成精化科技有限公司 2021-03-04 WO disclosed
CN-110423226-B Preparation method of 4-methyl-5-alkoxy oxazole 山东新和成精化科技有限公司 2021-01-05 CN disclosed
US-9796641-B2 Stabilization of radiosynthetic intermediates TRASIS S.A. (BE) 2017-10-24 US disclosed
WO-2009105513-A2 NOVEL COMPOUNDS AND METHODS FOR THERAPY GILEAD SCIENCES, INC. (US) 2009-08-27 WO disclosed
US-20030100790-A1 Process for preparing N-formylamino carboxylic esters BASF AKTIENGESELLSCHAFT (DE) 2003-05-29 US disclosed
EP-1310481-A1 Process for the preparation of N-formyl-aminocarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2003-05-14 EP disclosed
EP-0080119-B1 PROCESS FOR THE PREPARATION OF N-FORMYL-ALPHA-AMINO-ACID ESTERS BASF Aktiengesellschaft (DE) 1985-06-19 EP disclosed
EP-0080119-A1 Process for the preparation of N-formyl-alpha-amino-acid esters BASF Aktiengesellschaft (DE) 1983-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030100790-A1 Process for preparing N-formylamino carboxylic esters DNPEP, QPCT, FPR3 MGAM 928/4885GAA 2621/4885SI 153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.