SCHEMBL56388

SCHEMBL56388

O=C1c2ccccc2C(=O)c2cc3c(cc21)CCCC3

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
CDC25B P30305 2/20 0.55
BCL2 P10415 1/20 0.52
MCL1 Q07820 1/20 0.52
NPC1 O15118 5/20 0.48
RAB9A P51151 5/20 0.48
ALDH1A1 P00352 5/20 0.48
MAPK1 P28482 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
LMNA P02545 3/20 0.48
MAPT P10636 2/20 0.48
MAOA P21397 3/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
TP53 P04637 2/20 0.48
CYP3A4 P08684 2/20 0.48
ELANE P08246 1/20 0.48
CYP2A6 P11509 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30950751 1.00 MEN1 (0.55) MEN1KMT2ACDC25BBCL2MCL1
SCHEMBL29842380 1.00 MEN1 (0.55) MEN1KMT2ACDC25BBCL2MCL1
SCHEMBL16939654 0.88 CDC25B (0.64) MEN1KMT2ACDC25BALDH1A1MAPK1
SCHEMBL9149950 0.83 CES1 (0.50) MEN1KMT2ABCL2MCL1NPC1
Anthraquinone SCHEMBL29849898 0.81 MAOA (0.64) MEN1KMT2ACDC25BBCL2MCL1
SCHEMBL10824118 0.79 CYP2A6 (0.55) MEN1KMT2ACDC25BBCL2MCL1
Anthraquinone SCHEMBL27997409 0.78 MEN1 (0.63) MEN1KMT2ACDC25BBCL2MCL1
Anthraquinone SCHEMBL28961658 0.77 CDC25B (0.80) MEN1KMT2ACDC25BBCL2MCL1
Anthraquinone SCHEMBL28260408 0.77 MEN1 (0.92) MEN1KMT2ACDC25BBCL2MCL1
SCHEMBL11144928 0.76 CES1 (0.73) MEN1KMT2ACDC25BNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 439 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62195329-A None JP disclosed
US-20260069687-A1 THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER ASTELLAS PHARMA INC (JP) 2026-03-12 US disclosed
EP-3738611-B1 DIAGNOSIS AND THERAPY OF CANCER INVOLVING CANCER STEM CELLS BioNTech SE (DE) 2025-09-03 EP disclosed
EP-4556070-A2 COMBINATION THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER Astellas Pharma, Inc. (JP) 2025-05-21 EP disclosed
EP-4556071-A2 COMBINATION THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER Astellas Pharma, Inc. (JP) 2025-05-21 EP disclosed
US-20250092469-A1 METHODS AND COMPOSITIONS FOR PREDICTION OF THERAPEUTIC EFFICACY OF CANCER TREATMENTS AND CANCER PROGNOSIS GANYMED PHARMACEUTICALS GMBH (DE) 2025-03-20 US disclosed
US-12188097-B2 Methods and compositions for prediction of therapeutic efficacy of cancer treatments and cancer prognosis ASTELLAS PHARMA INC. (JP) 2025-01-07 US disclosed
US-20240335533-A1 COMBINATION THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER GANYMED PHARMACEUTICALS GMBH (DE) 2024-10-10 US disclosed
US-12059464-B2 Combination therapy involving antibodies against Claudin 18.2 for treatment of cancer ASTELLAS PHARMA INC. (JP) 2024-08-13 US disclosed
US-20240190991-A1 COMBINATION THERAPY WITH AN ANTI-CA19-9 ANTIBODY AND FOLFIRINOX IN THE TREATMENT OF CANCER BioNTech SE (DE) 2024-06-13 US disclosed
EP-0210638-A2 Optical coating composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-02-04 EP disclosed
US-4613560-A PHOTORESISTS, SEMICONDUCTORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-09-23 US disclosed
US-4601970-A Dry photosensitive film containing crosslinked beads E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-22 US disclosed
EP-0186163-A2 Photosensitive ceramic coating composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-02 EP disclosed
EP-0186114-A2 Photosensitive conductive metal composition E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-02 EP disclosed
US-4598037-A FIREABLE COATING OF SMOOTH METAL AND GLASS PARTICLES IN AN ACRYLICPHOTORESIST SYSTEM;ELECTRICAL THICK FILMS;RESOLUTIUON E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-07-01 US disclosed
US-4551415-A DRY FILM PHOTORESIST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-11-05 US disclosed
EP-0071483-B1 AMINONAPHTHACENE DERIVATIVES AND THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-01-02 EP disclosed
EP-0072259-B1 AMINONAPHTHACENE DERIVATIVES, THEIR PRODUCTION AND ANTI-TUMOR OR ANTI-MICROBIAL COMPOSITIONS CONTAINING THEM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1984-11-21 EP disclosed
EP-0092783-A2 Photosensitive coatings containing crosslinked beads E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190991-A1 COMBINATION THERAPY WITH AN ANTI-CA19-9 ANTIBODY AND FOLFIRINOX IN THE TREATMENT OF CANCER CA9, CA14, CA13 MEN1 1506/4885KMT2A 2507/4885CDC25B 2273/4885
US-20250092469-A1 METHODS AND COMPOSITIONS FOR PREDICTION OF THERAPEUTIC EFFICACY OF CANCER TREATMENTS AND CANCER PROGNOSIS TP53, MKI67, TSG101 MEN1 2987/4885KMT2A 3412/4885CDC25B 549/4885
US-12188097-B2 Methods and compositions for prediction of therapeutic efficacy of cancer treatments and cancer prognosis TP53, MKI67, TSG101 MEN1 2987/4885KMT2A 3412/4885CDC25B 549/4885
US-12059464-B2 Combination therapy involving antibodies against Claudin 18.2 for treatment of cancer EPCAM, KRT18, CALU MEN1 1562/4885KMT2A 2238/4885CDC25B 1046/4885
US-20240335533-A1 COMBINATION THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER EPCAM, KRT18, CALU MEN1 1562/4885KMT2A 2238/4885CDC25B 1046/4885
US-20260069687-A1 THERAPY INVOLVING ANTIBODIES AGAINST CLAUDIN 18.2 FOR TREATMENT OF CANCER EPCAM, VSIG8, ICAM1 MEN1 2443/4885KMT2A 2524/4885CDC25B 2047/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.