Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998200 | 0.81 | GAA (0.33) | GAA | |
| SCHEMBL5640472 | 0.81 | GAA (0.41) | GAAMDM2KDM4EMAPT | |
| SCHEMBL6383834 | 0.79 | TP53 (0.38) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL5640101 | 0.78 | ALDH1A1 (0.38) | RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL5639859 | 0.77 | GAA (0.39) | GAACYP1A2CYP2D6CYP2C19CYP19A1 | |
| SCHEMBL6995475 | 0.74 | ALDH1A1 (0.35) | ALDH1A1MAPT | |
| SCHEMBL5638232 | 0.69 | — | — | |
| SCHEMBL5637074 | 0.66 | GAA (0.36) | GAAMDM2KDM4E | |
| SCHEMBL6384929 | 0.62 | CYP1A2 (0.40) | CYP1A2CYP2D6CYP2C19CYP19A1CYP2C9 | |
| SCHEMBL6383214 | 0.62 | MDM2 (0.37) | GAACYP1A2CYP2D6CYP2C19CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301034-B2 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-27 | — | — | US | claimed |
| EP-1301469-B1 | PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES | BASF AG (DE) | 2006-06-21 | — | — | EP | claimed |
| US-20030149276-A1 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-07 | — | — | US | claimed |
| US-7301034-B2 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2007-11-27 | — | — | US | disclosed |
| EP-1301469-B1 | PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES | BASF AG (DE) | 2006-06-21 | — | — | EP | disclosed |
| US-20030149276-A1 | Preparation of -4-thioalkybrobenzene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149276-A1 | Preparation of -4-thioalkybrobenzene derivatives | CBR1, CBR3, AOC3 | GAA 4487/4885CYP1A2 253/4885CYP2D6 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.