SCHEMBL5638232

SCHEMBL5638232

CCc1c(Br)ccc(SC)c1C1=NOCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6995825 0.91
SCHEMBL701014 0.82
SCHEMBL6384937 0.81
SCHEMBL6982486 0.81
SCHEMBL5638953 0.81
SCHEMBL5637534 0.78 TUBB4A (0.32)
SCHEMBL701516 0.76
SCHEMBL6989149 0.73
SCHEMBL30480757 0.70 ALOX15 (0.31)
SCHEMBL5638801 0.69 GAA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7301034-B2 Preparation of -4-thioalkybrobenzene derivatives BASF AKTIENGESELLSCHAFT (DE) 2007-11-27 US claimed
EP-1301469-B1 PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES BASF AG (DE) 2006-06-21 EP claimed
US-20030149276-A1 Preparation of -4-thioalkybrobenzene derivatives BASF AKTIENGESELLSCHAFT (DE) 2003-08-07 US claimed
US-7301034-B2 Preparation of -4-thioalkybrobenzene derivatives BASF AKTIENGESELLSCHAFT (DE) 2007-11-27 US disclosed
EP-1301469-B1 PREPARATION OF 4-THIOALKYLBROMOBENZENE DERIVATIVES BASF AG (DE) 2006-06-21 EP disclosed
US-20030149276-A1 Preparation of -4-thioalkybrobenzene derivatives BASF AKTIENGESELLSCHAFT (DE) 2003-08-07 US disclosed