Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5639969 | 0.79 | PPARD (0.54) | PPARDPPARAPPARGBCHEACHE | |
| SCHEMBL5638277 | 0.78 | CYP1A2 (0.36) | LMNAMAPTL3MBTL1 | |
| SCHEMBL5640170 | 0.76 | PPARD (0.50) | PPARDPPARAPPARGBCHEACHE | |
| SCHEMBL5639325 | 0.75 | PTPRG (0.52) | DAOMAPTMAOBL3MBTL1 | |
| SCHEMBL6489922 | 0.71 | PPARD (0.48) | PPARDPPARAPPARGBCHELMNA | |
| SCHEMBL5728665 | 0.71 | PPARD (0.55) | PPARDPPARAPPARG | |
| SCHEMBL28944627 | 0.68 | BCHE (0.56) | PPARDPPARABCHEACHEDAO | |
| SCHEMBL6490179 | 0.68 | RAB9A (0.49) | LMNADAOMAPTMAOBL3MBTL1 | |
| SCHEMBL6901685 | 0.68 | MEN1 (0.49) | LMNADAOMAPTMAOBL3MBTL1 | |
| SCHEMBL3028480 | 0.67 | PDE2A (0.42) | DAOMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244763-B2 | Compounds that modulate PPAR activity and methods of preparation | WARNER LAMBERT COMPANY LLC (US) | 2007-07-17 | — | — | US | disclosed |