Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 9/20 | 0.55 |
| ▸ | PPARA | Q07869 | 6/20 | 0.55 |
| ▸ | PPARG | P37231 | 3/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 8/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPRB | P23467 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728669 | 0.88 | PPARD (0.55) | PPARDPPARAPPARGABCB1PTPRC | |
| SCHEMBL6493346 | 0.85 | PPARD (0.60) | PPARDPPARAPPARGPTPRCPTPN2 | |
| SCHEMBL3811706 | 0.85 | PPARD (0.77) | PPARDPPARAPPARGPTPN1FFAR4 | |
| SCHEMBL5512756 | 0.84 | PPARD (0.65) | PPARDPPARAPPARGFFAR4FFAR1 | |
| SCHEMBL5994374 | 0.76 | PPARD (0.53) | PPARDPPARAPPARGABCB1 | |
| SCHEMBL30889094 | 0.73 | APP (0.63) | ABCB1PTPRCPTPN2PTPN1PTPRB | |
| SCHEMBL5639337 | 0.71 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL1602178 | 0.71 | PPARD (1.00) | PPARDPPARAPPARG | |
| SCHEMBL5513388 | 0.71 | PPARD (0.83) | PPARDPPARAPPARG | |
| SCHEMBL2865421 | 0.70 | RXRA (0.56) | PTPRCPTPN2PTPN1PTPRBPTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727541-A1 | IMIDAZOLE-BASED HMG-COA REDUCTASE INHIBITORS | Warner-Lambert Company LLC (US) | 2006-12-06 | — | — | EP | disclosed |
| EP-1691803-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | Warner-Lambert Company LLC (US) | 2006-08-23 | — | — | EP | disclosed |
| WO-2005079790-A1 | IMIDAZOLE-BASED HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-09-01 | — | — | WO | disclosed |
| WO-2005056004-A1 | N-ALKYL PYRROLES AS HMG-COA REDUCTASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-06-23 | — | — | WO | disclosed |