Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8222117 | 0.77 | SMN1; SMN2 (0.46) | MEN1CYP2D6CYP2C19KMT2ACHRNB2 | |
| SCHEMBL5639789 | 0.73 | BAZ2A (0.42) | MEN1CYP2D6CYP2C19KMT2ACHRNB2 | |
| SCHEMBL8221171 | 0.71 | RAB9A (0.47) | CHRNB2CHRNA7CHRNA4SMN1; SMN2 | |
| SCHEMBL30555379 | 0.71 | RAB9A (0.47) | CHRNB2CHRNA7CHRNA4SMN1; SMN2 | |
| SCHEMBL2306060 | 0.71 | SMN1; SMN2 (0.44) | MEN1CYP2D6CYP2C19KMT2ACHRNB2 | |
| SCHEMBL2306066 | 0.71 | SMN1; SMN2 (0.44) | MEN1CYP2D6CYP2C19KMT2ACHRNB2 | |
| SCHEMBL2310395 | 0.69 | KDM4E (0.46) | MEN1CYP2D6CYP2C19KMT2ACHRNB2 | |
| SCHEMBL2310391 | 0.69 | KDM4E (0.46) | MEN1CYP2D6CYP2C19KMT2ACHRNB2 | |
| SCHEMBL2311560 | 0.68 | CPT2 (0.47) | MEN1CYP2D6CYP2C19KMT2ACHRNB2 | |
| SCHEMBL2311565 | 0.68 | CPT2 (0.47) | MEN1CYP2D6CYP2C19KMT2ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7173137-B2 | Epothilone analogs | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-02-06 | — | — | US | disclosed |
| US-20040127432-A1 | Epothilone analogs | THE SCRIPPS RESEARCH INSTITUTE | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127432-A1 | Epothilone analogs | TUBB8B, TUBB1, TUBA1B | MEN1 1099/4885CYP2D6 3348/4885CYP2C19 4540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.