⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757718 | 0.70 | — | — | |
| SCHEMBL2925217 | 0.69 | — | — | |
| SCHEMBL3956654 | 0.64 | PNMT (0.31) | — | |
| SCHEMBL30220101 | 0.64 | — | — | |
| SCHEMBL8984087 | 0.61 | — | — | |
| SCHEMBL581338 | 0.59 | — | — | |
| SCHEMBL24783963 | 0.58 | MEN1 (0.37) | — | |
| SCHEMBL15120307 | 0.58 | HTR5A (0.35) | — | |
| SCHEMBL29904252 | 0.58 | — | — | |
| SCHEMBL14733941 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0452002-A2 | Thienopyrimidine derivatives | DOWELANCO (US) | 1991-10-16 | — | — | EP | claimed |
| EP-0008408-B1 | 1,2,3,5-TETRAHYDROIMIDAZOTHIENOPYRIMIDIN-2-ONES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | DAIICHI SEIYAKU CO., LTD. (JP) | 1981-12-09 | — | — | EP | claimed |
| WO-2026106929-A1 | DIHYDROQUINAZOLINES USEFUL AS CYTOMEGALOVIRUS ANTIVIRAL AGENTS | ASSEMBLY BIOSCIENCES, INC. (US) | 2026-05-21 | — | — | WO | disclosed |
| EP-3753942-B1 | CRYSTAL FORM OF 3,4-DIHYDROTHIENO[3,2-D]PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR | PHAENO THERAPEUTICS CO LTD (CN) | 2024-01-03 | — | — | EP | disclosed |
| EP-3753942-B1 | CRYSTAL FORM OF 3,4-DIHYDROTHIENO[3,2-D]PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR | PHAENO THERAPEUTICS CO LTD (CN) | 2024-01-03 | — | — | EP | disclosed |
| US-11174270-B2 | Crystal form of 3,4-dihydrothieno[3,2-d]pyrimidine compound and preparation method thereof | PHAENO THERAPEUTICS CO., LTD. (CN) | 2021-11-16 | — | — | US | disclosed |
| US-11174270-B2 | Crystal form of 3,4-dihydrothieno[3,2-d]pyrimidine compound and preparation method thereof | PHAENO THERAPEUTICS CO., LTD. (CN) | 2021-11-16 | — | — | US | disclosed |
| US-11174270-B2 | Crystal form of 3,4-dihydrothieno[3,2-d]pyrimidine compound and preparation method thereof | PHAENO THERAPEUTICS CO., LTD. (CN) | 2021-11-16 | — | — | US | disclosed |
| CN-111741960-B | Crystal form of 3, 4-dihydrothieno [3,2-d ] pyrimidine compound and preparation method thereof | 南京明德新药研发有限公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-111741960-B | Crystal form of 3, 4-dihydrothieno [3,2-d ] pyrimidine compound and preparation method thereof | 南京明德新药研发有限公司 | 2021-06-25 | — | — | CN | disclosed |
| US-20210024538-A1 | Crystal Form of 3,4-Dihydrothieno[3,2-D]Pyrimidine Compound and Preparation Method Thereof | PHAENO THERAPEUTICS CO., LTD. (CN) | 2021-01-28 | — | — | US | disclosed |
| US-9486448-B2 | Pyrrolidine derived beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9486448-B2 | Pyrrolidine derived beta 3 adrenergic receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20160235727-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2016-08-18 | — | — | US | disclosed |
| US-20160235727-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2016-08-18 | — | — | US | disclosed |
| WO-2015050798-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-04-09 | — | — | WO | disclosed |
| US-7285556-B2 | Thienopyrimidine-based inhibitors of the src family | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMS (US) | 2007-10-23 | — | — | US | disclosed |
| US-20040077663-A1 | Thienopyrimidine-based inhibitors of the src family | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-22 | — | — | US | disclosed |
| EP-0452002-A2 | Thienopyrimidine derivatives | DOWELANCO (US) | 1991-10-16 | — | — | EP | disclosed |
| EP-0008408-B1 | 1,2,3,5-TETRAHYDROIMIDAZOTHIENOPYRIMIDIN-2-ONES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS | DAIICHI SEIYAKU CO., LTD. (JP) | 1981-12-09 | — | — | EP | disclosed |