Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.45 |
| ▸ | PGR | P06401 | 4/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645631 | 0.84 | NR3C1 (0.48) | NR3C1PGR | |
| SCHEMBL5643349 | 0.83 | NR3C1 (0.59) | NR3C1PGRNR3C2AR | |
| SCHEMBL4622178 | 0.82 | NR3C1 (0.49) | NR3C1PGR | |
| SCHEMBL5641687 | 0.78 | NR3C1 (0.60) | NR3C1PGRNR3C2AR | |
| SCHEMBL5641657 | 0.77 | NR3C1 (0.61) | NR3C1PGRNR3C2AR | |
| SCHEMBL4622431 | 0.77 | NR3C1 (0.45) | NR3C1PGRNR3C2AR | |
| SCHEMBL7172663 | 0.76 | NR3C1 (0.60) | NR3C1PGRNR3C2AR | |
| SCHEMBL6585728 | 0.76 | NR3C1 (0.51) | NR3C1PGR | |
| SCHEMBL5077893 | 0.76 | NR3C1 (0.48) | NR3C1PGRNR3C2AR | |
| SCHEMBL4622424 | 0.76 | NR3C1 (0.57) | NR3C1PGRNR3C2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166592-B2 | Antiinflammatory agents | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-01-23 | — | — | US | disclosed |
| US-7129270-B2 | Nonsteroidal antiinflammatory agents | Schėring AG (DE) | 2006-10-31 | — | — | US | disclosed |
| US-20060040933-A1 | Nonsteroidal antiinflammatory agents | JAROCH STEFAN | 2006-02-23 | — | — | US | disclosed |
| US-20040254249-A1 | Nonsteroidal antiinflammatory agents | JAROCH STEFAN (DE) | 2004-12-16 | — | — | US | disclosed |
| US-6777409-B2 | FOR THERAPY OF INFLAMMATION | SCHERING AKTIENGESELLSCHAFT PATENTS (DE) | 2004-08-17 | — | — | US | disclosed |
| EP-1309571-A1 | NON-STEROIDAL INFLAMMATION INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-14 | — | — | EP | disclosed |
| US-20020077356-A1 | Nonsteroidal antiinflammatory agents | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-06-20 | — | — | US | disclosed |
| WO-2002010143-A1 | NON-STEROIDAL INFLAMMATION INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020077356-A1 | Nonsteroidal antiinflammatory agents | PTGS1, PTGES2, PTGES | NR3C1 98/4885PGR 1776/4885NR3C2 155/4885 |
| US-20060040933-A1 | Nonsteroidal antiinflammatory agents | PTGES, PTGES2, PTGS1 | NR3C1 150/4885PGR 1229/4885NR3C2 156/4885 |
| US-20040254249-A1 | Nonsteroidal antiinflammatory agents | PTGS1, PTGER1, PTGES2 | NR3C1 135/4885PGR 2398/4885NR3C2 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.