Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.66 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.61 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366701 | 0.87 | OXTR (0.82) | OXTRAVPR1AMAPTTP53KMT2A | |
| SCHEMBL12675098 | 0.87 | OXTR (0.74) | OXTRMAPTTP53KMT2ATSHR | |
| SCHEMBL21033438 | 0.80 | MAPT (0.72) | OXTRAVPR1AMAPTTSHRPOLB | |
| SCHEMBL18958904 | 0.80 | MEN1 (0.63) | OXTRMAPTTP53KMT2A | |
| SCHEMBL18963016 | 0.78 | MAPT (0.79) | OXTRAVPR1AMAPTTP53KMT2A | |
| SCHEMBL16557491 | 0.78 | MAPT (0.66) | OXTRAVPR1AMAPTTP53KMT2A | |
| SCHEMBL744176 | 0.78 | OXTR (1.00) | OXTRAVPR1AMAPTTP53KMT2A | |
| SCHEMBL18962715 | 0.75 | KMT2A (0.62) | OXTRMAPTTP53KMT2AHCRTR1 | |
| SCHEMBL17340103 | 0.74 | TP53 (0.74) | OXTRAVPR1AMAPTTP53KMT2A | |
| SCHEMBL16557554 | 0.74 | MAPT (0.72) | MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |