Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 3/20 | 1.00 |
| ▸ | AVPR1A | P37288 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | TP53 | P04637 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366701 | 0.90 | OXTR (0.82) | OXTRAVPR1AMAPTTP53LMNA | |
| SCHEMBL16557537 | 0.87 | OXTR (0.77) | OXTRAVPR1AMAPTTP53LMNA | |
| SCHEMBL10005188 | 0.87 | OXTR (0.77) | OXTRAVPR1AMAPTTP53LMNA | |
| SCHEMBL5643910 | 0.83 | OXTR (1.00) | OXTRAVPR1AMAPTTP53LMNA | |
| SCHEMBL798403 | 0.82 | OXTR (0.69) | OXTRAVPR1AMAPTTP53LMNA | |
| SCHEMBL21033687 | 0.81 | MEN1 (0.76) | OXTRAVPR1AMAPTTP53LMNA | |
| SCHEMBL3432764 | 0.81 | MAPT (0.72) | OXTRAVPR1AMAPTLMNAHTT | |
| SCHEMBL10053474 | 0.80 | MAPT (0.69) | OXTRAVPR1AMAPTTP53LMNA | |
| SCHEMBL17340100 | 0.80 | MAPT (0.68) | OXTRAVPR1AMAPTTP53LMNA | |
| SCHEMBL806656 | 0.80 | MAPT (0.74) | OXTRAVPR1AMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138356-B2 | Chemical inhibitors of inhibitors of differentiation | Angiogeney, Inc. (US) | 2012-03-20 | — | — | US | disclosed |
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |
| US-7312358-B2 | Pharmaceutically active sulfanilide derivatives | LABORATOIRES SERONO SA (CH) | 2007-12-25 | — | — | US | disclosed |