SCHEMBL564428

SCHEMBL564428

Cc1ccc(-c2ccccn2)nc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.70
CCR5 P51681 3/20 0.70
CCR8 P51685 3/20 0.70
HDAC6 Q9UBN7 1/20 0.70
KDM4E B2RXH2 7/20 0.61
LMNA P02545 3/20 0.61
P4HTM Q9NXG6 2/20 0.61
CYP1A2 P05177 1/20 0.61
POLB P06746 1/20 0.61
METAP1 P53582 1/20 0.61
BLM P54132 1/20 0.61
HIF1A Q16665 1/20 0.61
DOHH Q9BU89 1/20 0.61
TP53 P04637 5/20 0.58
NPC1 O15118 4/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
RAB9A P51151 3/20 0.58
PKM P14618 3/20 0.58
ALOX15 P16050 2/20 0.58
HTT P42858 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30492588 1.00 CCR1 (0.70) CCR1CCR5CCR8HDAC6KDM4E
SCHEMBL13792039 0.96 CCR1 (0.64) CCR1CCR5CCR8HDAC6KDM4E
SCHEMBL14473534 0.92 KDM4E (0.67) CCR1CCR5CCR8HDAC6KDM4E
SCHEMBL17055534 0.90 CYP2A6 (0.58) CCR1CCR5CCR8HDAC6KDM4E
SCHEMBL12628229 0.88 KDM4E (0.67) CCR1CCR5CCR8HDAC6KDM4E
SCHEMBL15029845 0.88 CYP2A6 (0.56) CCR1CCR5CCR8HDAC6KDM4E
SCHEMBL10033056 0.88 TP53 (0.67) CCR1CCR5CCR8HDAC6KDM4E
SCHEMBL12628241 0.88 KDM4E (0.55) CCR1CCR5CCR8HDAC6KDM4E
SCHEMBL12628249 0.86 CCR1 (0.52) CCR1CCR5CCR8HDAC6KDM4E
SCHEMBL21022948 0.85 CYP2A6 (0.57) CCR1CCR5CCR8HDAC6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 372 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
CN-110416586-B Iron-based flow battery, positive and negative electrolyte thereof and preparation method 江西理工大学 2020-09-11 CN claimed
CN-111518145-A Cyanide-bridged metal organic compound with intramolecular magnetic transformation, and preparation method and application thereof 荆楚理工学院 2020-08-11 CN claimed
CN-110416586-A Iron-based flow battery and its positive and negative anodes electrolyte and preparation method UNIV JIANGXI SCI & TECHNOLOGY 2019-11-05 CN claimed
EP-0853064-B1 Process for the synthesis of hydrogen peroxide ENICHEM SPA (IT) 2000-02-23 EP claimed
EP-0808796-B1 Process for the preparation of hydrogen peroxide ENICHEM SPA (IT) 2000-02-09 EP claimed
EP-0728791-B1 Process for the preparation of copolymers based on carbon monoxide and at least one compound having an alkenylic unsaturation ENICHEM SPA (IT) 1999-06-23 EP claimed
EP-0894783-A1 Process for the synthesis of phenol from benzene Enichem S.p.A. (IT) 1999-02-03 EP claimed
US-5783164-A PALLADIUM CATALYST WITH A NITROGENATED LIGAND STABLE TO OXIDATION ENICHEM S.P.A. (IT) 1998-07-21 US claimed
EP-0853064-A1 Process for the synthesis of hydrogen peroxide ENICHEM S.p.A. (IT) 1998-07-15 EP claimed
US-5739264-A Process for the preparation of copolymers based on carbon monoxide and at least one compound having an alkenylic unsaturation ENICHEM S.P.A. (IT) 1998-04-14 US claimed
US-5734010-A Process for the preparation of copolymers of carbon monoxide and at least one compound containing an alkenyl unsaturation ENICHEM S.P.A. (IT) 1998-03-31 US claimed
EP-0808796-A1 Process for the preparation of hydrogen peroxide ENICHEM S.p.A. (IT) 1997-11-26 EP claimed
EP-0802213-A2 Process for the preparation of copolymers of carbon monoxide and at least one compound containing an alkenyl unsaturation ENICHEM S.p.A. (IT) 1997-10-22 EP claimed
EP-0728791-A1 Process for the preparation of copolymers based on carbon monoxide and at least one compound having an alkenylic unsaturation ENICHEM S.p.A. (IT) 1996-08-28 EP claimed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-11818932-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-14 US disclosed
EP-0610601-B1 Process for preparing polymers based on carbon monoxide and olefins ENICHEM SPA (IT) 1997-10-15 EP disclosed
EP-0728791-A1 Process for the preparation of copolymers based on carbon monoxide and at least one compound having an alkenylic unsaturation ENICHEM S.p.A. (IT) 1996-08-28 EP disclosed
EP-0610601-A1 Process for preparing polymers based on carbon monoxide and olefins ENICHEM S.p.A. (IT) 1994-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 CCR1 59/4885CCR5 584/4885CCR8 689/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.