Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971336 | 0.86 | SMN1; SMN2 (0.44) | MEN1KMT2APOLBDYRK1APDPK1 | |
| SCHEMBL3884988 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2AGAAIDO1HSD17B10 | |
| SCHEMBL17748324 | 0.78 | TDP1 (0.50) | MEN1KMT2APOLBDYRK1AGAA | |
| SCHEMBL3891134 | 0.78 | SMN1; SMN2 (0.38) | MEN1KMT2APOLBGAALMNA | |
| SCHEMBL975122 | 0.78 | ALDH1A1 (0.50) | MEN1KMT2APOLBDYRK1AGAA | |
| SCHEMBL11259370 | 0.77 | PKM (0.42) | MEN1KMT2AGAARAB9AHSD17B10 | |
| SCHEMBL1637554 | 0.77 | PTK2 (0.44) | MEN1KMT2ADYRK1AGAALMNA | |
| SCHEMBL2748592 | 0.77 | DYRK1A (0.44) | DYRK1ALMNARAB9AADORA3IDO1 | |
| SCHEMBL17220427 | 0.74 | NPC1 (0.43) | MEN1KMT2ADYRK1AGAALMNA | |
| SCHEMBL27971337 | 0.74 | IDO1 (0.44) | MEN1KMT2ARAB9AADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017189866-A1 | POLYMYXIN ANALOGS USEFUL AS ANTIBIOTIC POTENTIATORS | SPERO OPCO (US) | 2017-11-02 | — | — | WO | claimed |
| US-7166592-B2 | Antiinflammatory agents | SCHERING AKTIENGESELLSCHAFT (DE) | 2007-01-23 | — | — | US | claimed |
| WO-2017189866-A1 | POLYMYXIN ANALOGS USEFUL AS ANTIBIOTIC POTENTIATORS | SPERO OPCO (US) | 2017-11-02 | — | — | WO | disclosed |