Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5644991 | 0.81 | HPGD (0.53) | MTORMEN1KMT2ALIMK2EGLN1 | |
| SCHEMBL5646718 | 0.78 | LIMK2 (0.62) | MTORLIMK2ALOX5GAATRPM8 | |
| SCHEMBL11756196 | 0.75 | P2RX4 (0.49) | MEN1KMT2AGAATDP1SMN1; SMN2 | |
| SCHEMBL1520362 | 0.75 | MTOR (0.62) | MTORMEN1KMT2ALIMK2ALOX5 | |
| SCHEMBL6361997 | 0.75 | MEN1 (0.55) | MEN1KMT2AGAATDP1SMN1; SMN2 | |
| Benzene SCHEMBL28986126 | 0.75 | MTOR (0.62) | MTORMEN1KMT2ALIMK2ALOX5 | |
| SCHEMBL13740702 | 0.74 | PDK1 (0.64) | MTORMEN1KMT2ALIMK2GAA | |
| SCHEMBL4145996 | 0.74 | PDK1 (0.64) | MTORMEN1KMT2ALIMK2GAA | |
| SCHEMBL13740930 | 0.74 | PDK1 (0.64) | MTORMEN1KMT2ALIMK2GAA | |
| SCHEMBL6512237 | 0.73 | MTOR (0.61) | MTORLIMK2ALOX5GAATRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |