SCHEMBL56460

SCHEMBL56460

O=[N+]([O-])c1ccc(OCCO)cc1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.58
KCNH2 Q12809 3/20 0.55
DRD2 P14416 1/20 0.55
DRD4 P21917 1/20 0.55
DRD3 P35462 1/20 0.55
ALDH1A1 P00352 2/20 0.54
GAA P10253 2/20 0.54
TSHR P16473 2/20 0.53
PTGS2 P35354 2/20 0.53
LTA4H P09960 1/20 0.53
PTGS1 P23219 1/20 0.53
HRH3 Q9Y5N1 1/20 0.53
TDP1 Q9NUW8 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CRHBP P24387 1/20 0.52
CRHR2 Q13324 1/20 0.52
LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3345446 0.91 DRD2 (0.58) MAPTKCNH2DRD2DRD4DRD3
SCHEMBL9335745 0.90 PTGS2 (0.68) MAPTALDH1A1PTGS2PTGS1KDM4E
SCHEMBL9335748 0.90 PTGS2 (0.68) MAPTALDH1A1PTGS2PTGS1KDM4E
SCHEMBL9174886 0.90 MAPT (0.56) MAPTKCNH2DRD2DRD4DRD3
SCHEMBL31573176 0.90 MAPT (0.56) MAPTKCNH2DRD2DRD4DRD3
SCHEMBL31573181 0.90 MAPT (0.56) MAPTKCNH2DRD2DRD4DRD3
SCHEMBL31410110 0.90 MAPT (0.56) MAPTKCNH2DRD2DRD4DRD3
SCHEMBL7162702 0.90 MAPT (0.56) MAPTKCNH2DRD2DRD4DRD3
SCHEMBL31573185 0.90 MAPT (0.56) MAPTKCNH2DRD2DRD4DRD3
SCHEMBL28180218 0.90 MAPT (0.56) MAPTKCNH2DRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112979397-B Energy-containing adhesive based on three-dimensional photo-curing and preparation method thereof 辽宁省轻工科学研究院有限公司 2023-07-25 CN claimed
CN-111978553-B Triple-stimulus responsive interfacial crosslinked polymer micelle and preparation method and application thereof 陕西师范大学 2021-09-14 CN claimed
CN-111471185-B Triple-stimulus-responsive block polymer micelle and preparation method and application thereof 陕西师范大学 2021-09-14 CN claimed
CN-112979397-A Energy-containing adhesive based on three-dimensional photocuring and preparation method thereof 辽宁省轻工科学研究院有限公司 2021-06-18 CN claimed
CN-111978553-A Triple-stimulus responsive interfacial crosslinked polymer micelle and preparation method and application thereof 陕西师范大学 2020-11-24 CN claimed
CN-111471185-A Triple-stimulus-responsive block polymer micelle and preparation method and application thereof 陕西师范大学 2020-07-31 CN claimed
JP-11307398-A None JP disclosed
US-20250257069-A1 JAK INHIBITOR ANALOGS, FORMULATIONS, AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-08-14 US disclosed
EP-4561999-A1 TARGETED PROTEIN DEGRADATION OF PARP14 FOR USE IN THERAPY Abbvie Operations Singapore Pte. Ltd. (SG) 2025-06-04 EP disclosed
WO-2025097020-A1 PROCESS FOR POLYETHYLENE GLYCOL SYNTHESIS Design Therapeutics, Inc. (US) 2025-05-08 WO disclosed
CN-119923257-A JAK inhibitor analogues, formulations and uses thereof 密歇根大学董事会 2025-05-02 CN disclosed
CN-119923391-A Targeted protein degradation of PARP14 for use in therapy 艾伯维新加坡运营私人有限公司 2025-05-02 CN disclosed
WO-2025079518-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2025-04-17 WO disclosed
US-4277559-A FOR MASKING UNWANTED BLUE ABSORPTION OF MAGENTA DYES WITHOUT PRODUCING EXCESSIVE FOG AGFA-GEVAERT N.V. (BE) 1981-07-07 US disclosed
EP-0028331-A1 Process for preparing urethanes BAYER AG (DE) 1981-05-13 EP disclosed
EP-0027952-A1 Process for preparing N,O-disubstituted urethanes BAYER AG (DE) 1981-05-06 EP disclosed
EP-0027940-A1 Process for preparing urethanes BAYER AG (DE) 1981-05-06 EP disclosed
EP-0027953-A1 Process for preparing N,O-disubstituted urethanes BAYER AG (DE) 1981-05-06 EP disclosed
US-4138258-A NONDIFFUSING CYAN COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1979-02-06 US disclosed
US-4024159-A Process for the production of liquid acetals E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250257069-A1 JAK INHIBITOR ANALOGS, FORMULATIONS, AND USES THEREOF JAK1, JAK3, JAK2 MAPT 2679/4885KCNH2 4532/4885DRD2 4325/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.