SCHEMBL5646332

SCHEMBL5646332

S=C=Nc1c[c]ccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17414840 0.78 CYP3A4 (0.39)
SCHEMBL2838749 0.78
SCHEMBL457539 0.77
Phenylisothiocyanate SCHEMBL27304859 0.74 MIF (0.94)
SCHEMBL8314549 0.72
Phenylisothiocyanate SCHEMBL20984 0.71
SCHEMBL6286076 0.70
SCHEMBL11209386 0.70
SCHEMBL5014218 0.70
Phenylisothiocyanate SCHEMBL25197976 0.69 MIF (0.94)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1337520-B1 SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS CIBA SC HOLDING AG (CH) 2004-12-15 EP claimed
US-20040157966-A1 Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof PASTOR STEPHEN D (US) 2004-08-12 US claimed
US-20040092628-A1 Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparatiion thereof PASTOR STEPHEN D (US) 2004-05-13 US claimed
US-20030213164-A1 Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof PASTOR STEPHEN D (US) 2003-11-20 US claimed
US-6649770-B1 Exhibit superior hydrolytic stability, handling and storage stability as well as good resistance to extractability when present in stabilized composition CIBA SPECIALTY CHEMICALS CORPORATION 2003-11-18 US claimed
EP-1337520-A1 SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS Ciba SC Holding AG (CH) 2003-08-27 EP claimed
WO-2002042281-A1 SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-05-30 WO claimed
CN-111285918-B Metal/radiometal labeled PSMA inhibitors for PSMA-targeted imaging and radiation therapy 约翰霍普金斯大学 2024-05-31 CN disclosed
CN-111285918-A Metal/radiometal labeled PSMA inhibitors for PSMA-targeted imaging and radiotherapy 约翰霍普金斯大学 2020-06-16 CN disclosed
CN-106660943-B Metal/radiometal labeled PSMA inhibitors for PSMA-targeted imaging and radiotherapy 约翰霍普金斯大学 2020-03-17 CN disclosed
CN-110221063-A A kind of rapid time resolved fluorometric immunoassay detection kit and its detection method 广州市丰华生物工程有限公司 2019-09-10 CN disclosed
CN-106053783-A Quick time-resolved fluorescence immunoassay kit for detection of T cells infected with tuberculosis and detection method of kit 广州市丰华生物工程有限公司 2016-10-26 CN disclosed
US-7166659-B2 Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof CIBA SPECIALTY CHEMICALS CORPORATION (US) 2007-01-23 US disclosed
US-20040092628-A1 Substituted 5-aryl-2-(2-hydroxyphenyl)-2h-benzotriazole UV absorbers, compositions stabilized therewith and process for preparatiion thereof PASTOR STEPHEN D (US) 2004-05-13 US disclosed
US-6703510-B2 MORE STABLE AND DURABLE; AUTOMOTIVE COATINGS, CANDLE WAX CIBA SPECIALTY CHEMICALS CORPORATION 2004-03-09 US disclosed
US-20030213164-A1 Substituted 5-aryl-2-(2-hydroxyphenyl)-2H-benzotriazole UV absorbers, compositions stabilized therewith and process for preparation thereof PASTOR STEPHEN D (US) 2003-11-20 US disclosed
US-6649770-B1 Exhibit superior hydrolytic stability, handling and storage stability as well as good resistance to extractability when present in stabilized composition CIBA SPECIALTY CHEMICALS CORPORATION 2003-11-18 US disclosed
EP-1337520-A1 SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS Ciba SC Holding AG (CH) 2003-08-27 EP disclosed
WO-2002042281-A1 SUBSTITUTED 5-ARYL AND 5-HETEROARYL-2-(2-HYDROXYPHENYL)-2H-BENZOTRIAZOLE DERIVATIVES AS UV ABSORBERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-05-30 WO disclosed
WO-1995022576-A1 ADHESION SYSTEM BEAVER MANUFACTURING COMPANY, INC. (US) 1995-08-24 WO disclosed