SCHEMBL8314549

SCHEMBL8314549

S=C=Nc1c[c]c[c]c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL457539 0.68
Bitoscanate SCHEMBL157128 0.67 MIF (0.72)
SCHEMBL7387255 0.67 MIF (0.55)
Phenylisothiocyanate SCHEMBL27304859 0.65 MIF (0.94)
SCHEMBL1548531 0.61 MIF (0.62)
Phenylisothiocyanate SCHEMBL20984 0.61
SCHEMBL5629621 0.61 P2RY6 (0.42)
SCHEMBL8990792 0.60 GABRA1 (0.33)
SCHEMBL7390143 0.60 MIF (0.41)
SCHEMBL29286863 0.60 MIF (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5958373-A Polychelants as contrast enhancing agents NYCOMED SALUTAR INC. (US) 1999-09-28 US claimed
EP-0717737-B1 CHELANTS AS CONTRAST ENHANCING AGENTS NYCOMED SALUTAR INC (US) 1999-04-07 EP claimed
EP-0717737-A1 CHELANTS AS CONTRAST ENHANCING AGENTS NYCOMED SALUTAR, INC. (US) 1996-06-26 EP claimed
WO-1995007270-A1 CHELANTS AS CONTRAST ENHANCING AGENTS NYCOMED SALUTAR, INC. (US) 1995-03-16 WO claimed
US-5958373-A Polychelants as contrast enhancing agents NYCOMED SALUTAR INC. (US) 1999-09-28 US disclosed
EP-0717737-B1 CHELANTS AS CONTRAST ENHANCING AGENTS NYCOMED SALUTAR INC (US) 1999-04-07 EP disclosed
EP-0717737-A1 CHELANTS AS CONTRAST ENHANCING AGENTS NYCOMED SALUTAR, INC. (US) 1996-06-26 EP disclosed
WO-1995007270-A1 CHELANTS AS CONTRAST ENHANCING AGENTS NYCOMED SALUTAR, INC. (US) 1995-03-16 WO disclosed