Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.48 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.47 |
| ▸ | B3GNT2 | Q9NY97 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408988 | 0.86 | HDAC8 (0.56) | GPR139NR1H4HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL31498841 | 0.84 | GPR139 (0.72) | GPR139NR1H4HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL5643762 | 0.84 | ALDH1A1 (0.71) | GPR139NR1H4HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL7676189 | 0.84 | SMN1; SMN2 (0.71) | GPR139NR1H4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1922928 | 0.84 | SMN1; SMN2 (0.71) | GPR139NR1H4ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL507574 | 0.82 | ALDH1A1 (0.58) | GPR139NR1H4HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3031481 | 0.82 | CYP1A2 (0.58) | GPR139NR1H4HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL507256 | 0.82 | ALDH1A1 (0.58) | GPR139NR1H4HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL507255 | 0.82 | ALDH1A1 (0.58) | GPR139NR1H4HTTALDH1A1SMN1; SMN2 | |
| SCHEMBL3109453 | 0.80 | ROCK1 (0.75) | GPR139KMT2AMEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241759-B2 | Benzo[1,2,5]thiadiazole compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-10 | — | — | US | disclosed |