SCHEMBL564676

SCHEMBL564676

Nc1cc(S(=O)(=O)c2cccc(O)c2)ccc1O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.79
MAPT P10636 2/20 0.79
CA2 P00918 5/20 0.61
CA1 P00915 4/20 0.61
CA12 O43570 3/20 0.61
CA9 Q16790 3/20 0.61
ALDH1A1 P00352 4/20 0.59
HSD17B10 Q99714 1/20 0.59
LMNA P02545 1/20 0.50
HTR6 P50406 2/20 0.47
POLB P06746 1/20 0.46
GFER P55789 1/20 0.46
PKM P14618 3/20 0.46
HSD17B1 P14061 2/20 0.46
HSD17B2 P37059 2/20 0.46
ABCC9 O60706 1/20 0.44
ABCC8 Q09428 1/20 0.44
KCNJ11 Q14654 1/20 0.44
KCNJ8 Q15842 1/20 0.44
ANXA2 P07355 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL109925 0.89 GAA (1.00) GAAMAPTCA2CA1CA12
SCHEMBL1732796 0.89 GAA (1.00) GAAMAPTCA2CA1CA12
SCHEMBL29363328 0.89 GAA (1.00) GAAMAPTCA2CA1CA12
SCHEMBL29871288 0.89 GAA (1.00) GAAMAPTCA2CA1CA12
SCHEMBL565327 0.88 GAA (0.76) GAAMAPTCA2CA1CA12
SCHEMBL564658 0.88 GAA (0.59) GAAMAPTCA2CA1CA12
SCHEMBL565124 0.87 GAA (0.81) GAAMAPTCA2CA1CA12
Hydrochloric Acid SCHEMBL28556898 0.87 GAA (0.96) GAAMAPTCA2CA1CA12
Hydrochloric Acid SCHEMBL9447766 0.87 GAA (0.96) GAAMAPTCA2CA1CA12
SCHEMBL28269760 0.87 GAA (0.96) GAAMAPTCA2CA1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 GAA 3993/4885MAPT 3886/4885CA2 1653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.