SCHEMBL565124

SCHEMBL565124

Nc1cc(S(=O)(=O)c2ccccc2)ccc1O

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.81
MAPT P10636 4/20 0.81
CA2 P00918 3/20 0.63
CA12 O43570 2/20 0.63
CA1 P00915 2/20 0.63
CA9 Q16790 2/20 0.63
ALDH1A1 P00352 4/20 0.61
HSD17B10 Q99714 2/20 0.61
HTR6 P50406 6/20 0.52
PKM P14618 2/20 0.52
POLB P06746 2/20 0.51
GFER P55789 1/20 0.51
LMNA P02545 3/20 0.48
KDM4E B2RXH2 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
USP2 O75604 1/20 0.48
HSP90AA1 P07900 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29871288 0.90 GAA (1.00) GAAMAPTCA2CA12CA1
SCHEMBL109925 0.90 GAA (1.00) GAAMAPTCA2CA12CA1
SCHEMBL29363328 0.90 GAA (1.00) GAAMAPTCA2CA12CA1
SCHEMBL1732796 0.90 GAA (1.00) GAAMAPTCA2CA12CA1
Hydrochloric Acid SCHEMBL9447766 0.88 GAA (0.96) GAAMAPTCA2CA12CA1
Hydrochloric Acid SCHEMBL28556898 0.88 GAA (0.96) GAAMAPTCA2CA12CA1
SCHEMBL28269760 0.88 GAA (0.96) GAAMAPTCA2CA12CA1
SCHEMBL564676 0.87 GAA (0.79) GAAMAPTCA2CA12CA1
SCHEMBL565259 0.87 GAA (0.85) GAAMAPTCA2CA12CA1
SCHEMBL565062 0.87 GAA (0.85) GAAMAPTCA2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106498803-A A kind of paper grade (stock) sterilization antiseptic and preparation method thereof 金福英 2017-03-15 CN claimed
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME CHECKMATE THERAPEUTICS INC. (KR) 2026-01-22 US disclosed
WO-2023229346-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME 주식회사 체크메이트테라퓨틱스 2023-11-30 WO disclosed
WO-2023229346-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME 주식회사 체크메이트테라퓨틱스 2023-11-30 WO disclosed
US-10973831-B2 Fluoropiperidine compounds as pure 5-HT 6 receptor antagonists SUVEN LIFE SCIENCES LIMITED (IN) 2021-04-13 US disclosed
US-10973831-B2 Fluoropiperidine compounds as pure 5-HT 6 receptor antagonists SUVEN LIFE SCIENCES LIMITED (IN) 2021-04-13 US disclosed
CN-111051302-B Fluoropiperidine compounds as pure 5-HT 6receptor antagonists 苏文生命科学有限公司 2021-04-09 CN disclosed
EP-3649124-B1 FLUOROPIPERIDINE COMPOUNDS AS PURE 5-HT6 RECEPTOR ANTAGONISTS SUVEN LIFE SCIENCES LTD (IN) 2021-03-03 EP disclosed
EP-3649124-B1 FLUOROPIPERIDINE COMPOUNDS AS PURE 5-HT6 RECEPTOR ANTAGONISTS SUVEN LIFE SCIENCES LTD (IN) 2021-03-03 EP disclosed
US-20200155560-A1 FLUOROPIPERIDINE COMPOUNDS AS PURE 5-HT 6 RECEPTOR ANTAGONISTS SUVEN LIFE SCIENCES LIMITED (IN) 2020-05-21 US disclosed
EP-0054230-A2 Monoazo dyestuffs and use as image-forming dyestuffs in colour-photographic registration materials Agfa-Gevaert AG (DE) 1982-06-23 EP disclosed
US-4219473-A Substituted unsymmetrical azo, azomethine 1:2 chromium complexes CIBA-GEIGY CORPORATION (US) 1980-08-26 US disclosed
US-4125368-A Metallized monoazo dyes TOMS RIVER CHEMICAL CORP. (US) 1978-11-14 US disclosed
US-4086223-A Asymmetrical 1:2-chromium complex azo dyestuffs CIBA-GEIGY AG (CH) 1978-04-25 US disclosed
US-4058408-A Bis-benzoxazolyl-naphthalenes as optical brighteners CIBA-GEIGY CORPORATION (US) 1977-11-15 US disclosed
US-4058515-A Metallized phenyl-azo-naphthol compounds TOMS RIVER CHEMICAL CORPORATION (US) 1977-11-15 US disclosed
US-4053462-A UNSYMMETRICAL PHENYL AZO NAPHTHYL CHROMIUM COMPLEX DYES CIBA-GEIGY CORPORATION (US) 1977-10-11 US disclosed
US-4005065-A GOOD FASTNESS TO LIGHT, PERSPIRATION, FULLING, DECATIZING AND CARBONIZING CIBA-GEIGY CORPORATION (US) 1977-01-25 US disclosed
US-3993659-A Bis-benzoxazolyl-naphthalenes as optical brighteners CIBA-GEIGY CORPORATION (US) 1976-11-23 US disclosed
US-3985763-A DYESTUFFS BAYER AKTIENGESELLSCHAFT (DT) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200155560-A1 FLUOROPIPERIDINE COMPOUNDS AS PURE 5-HT 6 RECEPTOR ANTAGONISTS HTR6, HTR5A, HTR1B GAA 3728/4885MAPT 2944/4885CA2 3947/4885
US-10973831-B2 Fluoropiperidine compounds as pure 5-HT 6 receptor antagonists HTR6, HTR5A, HTR1B GAA 3728/4885MAPT 2944/4885CA2 3947/4885
US-20260022122-A1 NOVEL COMPOUND FOR INHIBITING NAMPT, AND COMPOSITION INCLUDING SAME NAMPT, NAPRT, NNT GAA 2409/4885MAPT 1402/4885CA2 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.